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Tuberculin Skin Test and Boosted Reactions among Newly Employed Healthcare Workers: An Observational Study

DC Field Value Language
dc.contributor.author김송이-
dc.contributor.author김영삼-
dc.contributor.author김현숙-
dc.contributor.author박무석-
dc.contributor.author용동은-
dc.contributor.author이경원-
dc.contributor.author장준-
dc.contributor.author강영애-
dc.contributor.author김세규-
dc.date.accessioned2014-12-18T08:49:28Z-
dc.date.available2014-12-18T08:49:28Z-
dc.date.issued2013-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/87019-
dc.description.abstractOBJECTIVE: To evaluate the prevalence of and factors associated with latent tuberculosis infection (LTBI) based on the tuberculin skin test (TST) and to estimate the boosted reaction rate among newly employed healthcare workers (HCWs). DESIGN: Newly employed HCWs between January 2010 and July 2012 at Severance Hospital in South Korea were enrolled in this study. A one-step TST was conducted before October 2011, and a two-step TST after October 2011. RESULTS: Of 2132 participants, 778 (36.5%) had positive TST results. Being older (odds ratio [OR] 1.10, 95% confidence interval [CI] 1.06-1.13, P<0.001), male (OR 1.78, 95% CI 1.21-2.62, P = 0.003), rejoining the hospital workforce (OR 1.58, 95% CI 1.04-2.40, P = 0.032), and having a previous history of tuberculosis (TB) (OR 18.21, 95% CI 2.15-154.10, P = 0.008) during the one-step period, and being older (OR 1.15, 95% CI 1.10-1.21, P<0.001) during the two-step period were significantly associated with a positive TST. A two-step TST was performed in 556 HCWs, and a boosted reaction was observed in 79 (14.2%). The induration size on the first TST (5-9-mm group) was the only factor associated with a boosted reaction on the second TST. CONCLUSIONS: The prevalence of LTBI based on the TST among newly employed HCWs was high. The boosted reaction rate on two-step TST was not low; therefore, the use of two-step TST may be necessary for regular monitoring in countries with an intermediate TB burden and a high rate of Bacillus Calmette-Guérin vaccination.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfPLOS ONE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHealth Personnel*-
dc.subject.MESHHumans-
dc.subject.MESHLatent Tuberculosis/diagnosis*-
dc.subject.MESHLatent Tuberculosis/epidemiology-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPrevalence-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.subject.MESHTuberculin Test*-
dc.subject.MESHYoung Adult-
dc.titleTuberculin Skin Test and Boosted Reactions among Newly Employed Healthcare Workers: An Observational Study-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorSong Yee Kim-
dc.contributor.googleauthorMoo Suk Park-
dc.contributor.googleauthorYoung Sam Kim-
dc.contributor.googleauthorSe Kyu Kim-
dc.contributor.googleauthorJoon Chang-
dc.contributor.googleauthorDong eun Yong-
dc.contributor.googleauthorHyun Sook Kim-
dc.contributor.googleauthorKyungwon Lee-
dc.contributor.googleauthorYoung Ae Kang-
dc.identifier.doi10.1371/journal.pone.0064563-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00626-
dc.contributor.localIdA00707-
dc.contributor.localIdA01457-
dc.contributor.localIdA02423-
dc.contributor.localIdA02649-
dc.contributor.localIdA03472-
dc.contributor.localIdA00057-
dc.contributor.localIdA00602-
dc.contributor.localIdA01117-
dc.relation.journalcodeJ02540-
dc.identifier.eissn1932-6203-
dc.identifier.pmid23717631-
dc.subject.keywordAdult-
dc.subject.keywordAged-
dc.subject.keywordFemale-
dc.subject.keywordFollow-Up Studies-
dc.subject.keywordHealth Personnel*-
dc.subject.keywordHumans-
dc.subject.keywordLatent Tuberculosis/diagnosis*-
dc.subject.keywordLatent Tuberculosis/epidemiology-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordPrevalence-
dc.subject.keywordRepublic of Korea/epidemiology-
dc.subject.keywordRetrospective Studies-
dc.subject.keywordRisk Factors-
dc.subject.keywordTuberculin Test*-
dc.subject.keywordYoung Adult-
dc.contributor.alternativeNameKim, Song Yi-
dc.contributor.alternativeNameKim, Young Sam-
dc.contributor.alternativeNameKim, Hyon Suk-
dc.contributor.alternativeNamePark, Moo Suk-
dc.contributor.alternativeNameYong, Dong Eun-
dc.contributor.alternativeNameLee, Kyung Won-
dc.contributor.alternativeNameChang, Joon-
dc.contributor.alternativeNameKang, Young Ae-
dc.contributor.alternativeNameKim, Se Kyu-
dc.contributor.affiliatedAuthorKim, Song Yi-
dc.contributor.affiliatedAuthorKim, Young Sam-
dc.contributor.affiliatedAuthorPark, Moo Suk-
dc.contributor.affiliatedAuthorYong, Dong Eun-
dc.contributor.affiliatedAuthorLee, Kyung Won-
dc.contributor.affiliatedAuthorChang, Joon-
dc.contributor.affiliatedAuthorKang, Young Ae-
dc.contributor.affiliatedAuthorKim, Se Kyu-
dc.contributor.affiliatedAuthorKim, Hyon Suk-
dc.rights.accessRightsfree-
dc.citation.volume8-
dc.citation.number5-
dc.citation.startPagee64563-
dc.identifier.bibliographicCitationPLOS ONE, Vol.8(5) : e64563, 2013-
dc.identifier.rimsid32101-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

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