Cited 59 times in
Clinical application of liver stiffness measurement using transient elastography in chronic liver disease from longitudinal perspectives
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김범경 | - |
dc.contributor.author | 김승업 | - |
dc.date.accessioned | 2014-12-18T08:46:20Z | - |
dc.date.available | 2014-12-18T08:46:20Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1007-9327 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/86923 | - |
dc.description.abstract | Accurate determination of the presence and degree of fibrosis in liver is of great importance, because the prognosis and management strategies for chronic liver disease depend mainly on these factors. To date, liver biopsy (LB) remains the “gold standard” for assessing the severity of liver fibrosis; however, LB is often limited by its invasiveness, sampling error, and intra/inter-observer variability in histological interpretation. Furthermore, repeated LB examinations within a short time interval are indeed ineligible in a real clinical practice. Thus, due to the pressing need for non-invasive surrogates for liver fibrosis, transient elastography (TE), as a novel ultrasound based technology, has allowed a noninvasive measurement of liver stiffness and has gained in popularity over recent years. In the past few years, additional roles for transient TE beyond the initial purpose of a non-invasive surrogate for LB have included the prediction of the most two critical consequences of fibrosis progression: the development of portal hypertension-related complications and hepatocellular carcinoma. This indicates that the role of transient TE is not merely limited to reducing the need for LB, but transient TE can enable the establishment of tailored management strategies by providing more detailed prognostic information. In particular, under the concept in which the clinical course of liver fibrosis is dynamic and bidirectional, especially when appropriate intervention is commenced, transient TE can be used to track the dynamic changes in fibrotic burden during antiviral or antifibrotic treatment. This review discussed extended applications of transient TE in prediction of the development of real clinical endpoints from a longitudinal perspective. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | WORLD JOURNAL OF GASTROENTEROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Antiviral Agents/therapeutic use | - |
dc.subject.MESH | Elasticity Imaging Techniques* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Liver Cirrhosis/complications | - |
dc.subject.MESH | Liver Cirrhosis/diagnosis* | - |
dc.subject.MESH | Liver Cirrhosis/drug therapy | - |
dc.subject.MESH | Prognosis | - |
dc.title | Clinical application of liver stiffness measurement using transient elastography in chronic liver disease from longitudinal perspectives | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Beom Kyung Kim | - |
dc.contributor.googleauthor | James Fung | - |
dc.contributor.googleauthor | Man-Fung Yuen | - |
dc.contributor.googleauthor | Seung Up Kim | - |
dc.identifier.doi | 10.3748/wjg.v19.i12.1890 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00487 | - |
dc.contributor.localId | A00654 | - |
dc.relation.journalcode | J02795 | - |
dc.identifier.eissn | 2219-2840 | - |
dc.identifier.pmid | 23569334 | - |
dc.subject.keyword | Fibroscan | - |
dc.subject.keyword | Fibrosis | - |
dc.subject.keyword | Liver stiffness | - |
dc.subject.keyword | Longitudinal | - |
dc.subject.keyword | Outcome | - |
dc.subject.keyword | Transient elastography | - |
dc.contributor.alternativeName | Kim, Beom Kyung | - |
dc.contributor.alternativeName | Kim, Seung Up | - |
dc.contributor.affiliatedAuthor | Kim, Beom Kyung | - |
dc.contributor.affiliatedAuthor | Kim, Seung Up | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 19 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1890 | - |
dc.citation.endPage | 1900 | - |
dc.identifier.bibliographicCitation | WORLD JOURNAL OF GASTROENTEROLOGY, Vol.19(12) : 1890-1900, 2013 | - |
dc.identifier.rimsid | 32036 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.