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Left ventricular diastolic function is closely associated with mechanical function of the left atrium in patients with paroxysmal atrial fibrillation.

DC FieldValueLanguage
dc.contributor.author박희남-
dc.contributor.author심지영-
dc.contributor.author위진-
dc.contributor.author이문형-
dc.contributor.author정보영-
dc.contributor.author하종원-
dc.date.accessioned2014-12-18T08:45:06Z-
dc.date.available2014-12-18T08:45:06Z-
dc.date.issued2013-
dc.identifier.issn1346-9843-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/86886-
dc.description.abstractBackground: Left ventricular (LV) diastolic dysfunction may be a mechanism of left atrial (LA) electroanatomical remodeling in atrial fibrillation (AF). We evaluated the association between LV diastolic function and LA mechanical function in non-valvular paroxysmal AF (PAF). Methods and Results: In 286 patients with PAF (males 73%, 57±11 years), LA size, indexed LA volume, LV diastolic function, and LA appendage flow velocity (LAA-FV) in sinus rhythm were measured using transthoracic echocardiography, transesophageal echocardiography and cardiac computed tomography. The LA voltage map was obtained using NavX contact mapping. Patients with impaired LA mechanical function (LAA-FV <58cm/s, n=142) showed a higher E/Em ratio (10.3 vs. 9.2, P=0.034) and lower Em velocity (6.8 vs. 7.7cm/s, P=0.004) than those with preserved function (LAA-FV ≥58cm/s, n=144). The patient population displayed weak correlations of E/Em with LAA-FV (r=-0.19, P=0.003) and LA voltage (r=-0.23, P=0.004), but more significant association of E/Em and LAA-FV (r=-0.39, P<0.001) for age ≥55 years and LA diameter ≥40mm. E/Em was an independent predictor of LAA mechanical function (β=-0.20, P=0.013) even after age, sex, LA size and comorbidities were controlled for. Conclusions: In patients with non-valvular PAF, LA mechanical function is closely related to the degree of LA remodeling and LV diastolic function. Impaired LV diastolic function significantly contributes to LA electoanatomical remodeling in older patients with a larger LA.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfCIRCULATION JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAtrial Fibrillation/diagnostic imaging-
dc.subject.MESHAtrial Fibrillation/physiopathology*-
dc.subject.MESHAtrial Function, Left/physiology*-
dc.subject.MESHEchocardiography-
dc.subject.MESHElectrophysiologic Techniques, Cardiac-
dc.subject.MESHFemale-
dc.subject.MESHHeart Atria/diagnostic imaging-
dc.subject.MESHHeart Atria/physiopathology-
dc.subject.MESHHeart Ventricles/diagnostic imaging-
dc.subject.MESHHeart Ventricles/physiopathology-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTomography, X-Ray Computed-
dc.subject.MESHVentricular Dysfunction, Left/diagnostic imaging-
dc.subject.MESHVentricular Dysfunction, Left/physiopathology*-
dc.titleLeft ventricular diastolic function is closely associated with mechanical function of the left atrium in patients with paroxysmal atrial fibrillation.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorJihei Sara Lee-
dc.contributor.googleauthorChi Young Shim-
dc.contributor.googleauthorJin Wi-
dc.contributor.googleauthorBoyoung Joung-
dc.contributor.googleauthorJong-Won Ha-
dc.contributor.googleauthorMoon Hyoung Lee-
dc.contributor.googleauthorHui-Nam Pak-
dc.identifier.doi10.1253/circj.CJ-12-1009-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01776-
dc.contributor.localIdA02213-
dc.contributor.localIdA02450-
dc.contributor.localIdA02766-
dc.contributor.localIdA03609-
dc.contributor.localIdA04257-
dc.relation.journalcodeJ00534-
dc.identifier.eissn1347-4820-
dc.identifier.pmid23196755-
dc.subject.keywordAtrial fibrillation-
dc.subject.keywordDiastolic function-
dc.subject.keywordElectroanatomical remodeling-
dc.subject.keywordLeft atrium-
dc.subject.keywordLeft ventricle-
dc.contributor.alternativeNamePak, Hui Nam-
dc.contributor.alternativeNameShim, Chi Young-
dc.contributor.alternativeNameWi, Jin-
dc.contributor.alternativeNameLee, Moon Hyoung-
dc.contributor.alternativeNameJoung, Bo Young-
dc.contributor.alternativeNameHa, Jong Won-
dc.contributor.affiliatedAuthorPak, Hui Nam-
dc.contributor.affiliatedAuthorShim, Chi Young-
dc.contributor.affiliatedAuthorWi, Jin-
dc.contributor.affiliatedAuthorLee, Moon Hyoung-
dc.contributor.affiliatedAuthorJoung, Bo Young-
dc.contributor.affiliatedAuthorHa, Jong Won-
dc.rights.accessRightsfree-
dc.citation.volume77-
dc.citation.number3-
dc.citation.startPage697-
dc.citation.endPage704-
dc.identifier.bibliographicCitationCIRCULATION JOURNAL, Vol.77(3) : 697-704, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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