Cited 11 times in
Transcriptional and epigenetic networks in the development and maturation of dendritic cells
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김형표 | - |
dc.date.accessioned | 2014-12-18T08:43:20Z | - |
dc.date.available | 2014-12-18T08:43:20Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1750-1911 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/86831 | - |
dc.description.abstract | Dendritic cells (DCs) are professional antigen-presenting cells that provide a critical link between the innate and adaptive immune responses. The genetic program required for differentiation of DCs from their hematopoietic precursors is controlled by both cytokines and transcription factors. The signals transduced from cytokines recruit specific transcription factors, enabling the expression of a distinct transcriptome that is required for specification of different DC lineages. The establishment of a distinct transcriptome also depends on chromatin modifications associated with critical cis elements of lineage-specific genes. In this review, recent advances in the understanding of the transcriptional network governing DC lineage specification are summarized, along with current views of the dynamic DC epigenome. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | EPIGENOMICS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adaptive Immunity/genetics | - |
dc.subject.MESH | Cell Differentiation/genetics* | - |
dc.subject.MESH | Cell Lineage | - |
dc.subject.MESH | Chromatin/genetics | - |
dc.subject.MESH | Chromatin/metabolism | - |
dc.subject.MESH | Cytokines/genetics | - |
dc.subject.MESH | Cytokines/metabolism | - |
dc.subject.MESH | Dendritic Cells*/cytology | - |
dc.subject.MESH | Dendritic Cells*/physiology | - |
dc.subject.MESH | Epigenesis, Genetic/genetics* | - |
dc.subject.MESH | Gene Regulatory Networks/genetics* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunity, Innate/genetics | - |
dc.subject.MESH | Signal Transduction | - |
dc.title | Transcriptional and epigenetic networks in the development and maturation of dendritic cells | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Environmental Medical Biology (환경의생물학) | - |
dc.contributor.googleauthor | Hyoung-Pyo Kim | - |
dc.contributor.googleauthor | Yeon-Su Lee | - |
dc.contributor.googleauthor | Jong Hoon Park | - |
dc.contributor.googleauthor | Young-Joon Kim | - |
dc.identifier.doi | 10.2217/epi.13.14 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01163 | - |
dc.relation.journalcode | J00792 | - |
dc.identifier.eissn | 1750-192X | - |
dc.identifier.pmid | 23566096 | - |
dc.identifier.url | http://www.futuremedicine.com/doi/abs/10.2217/epi.13.14?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed& | - |
dc.subject.keyword | chromatin | - |
dc.subject.keyword | dendritic cells | - |
dc.subject.keyword | DNA methylation | - |
dc.subject.keyword | epigenetic | - |
dc.subject.keyword | histone | - |
dc.subject.keyword | lineage | - |
dc.subject.keyword | transcriptional network | - |
dc.contributor.alternativeName | Kim, Hyoung Pyo | - |
dc.contributor.affiliatedAuthor | Kim, Hyoung Pyo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 5 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 195 | - |
dc.citation.endPage | 204 | - |
dc.identifier.bibliographicCitation | EPIGENOMICS, Vol.5(2) : 195-204, 2013 | - |
dc.identifier.rimsid | 29231 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.