Cited 5 times in
Incidence of and risk factors for active tuberculosis in human immunodeficiency virus-infected patients in South Korea
DC Field | Value | Language |
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dc.contributor.author | 구남수 | - |
dc.contributor.author | 김준명 | - |
dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2014-12-18T08:42:49Z | - |
dc.date.available | 2014-12-18T08:42:49Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/86816 | - |
dc.description.abstract | BACKGROUND: In South Korea, a high-income country with an intermediate tuberculosis (TB) burden and low human immunodeficiency virus (HIV) prevalence, studies on incidence and risk factors of TB in HIV-infected persons have rarely been reported. OBJECTIVE: To investigate the incidence of and risk factors for active TB in HIV-infected persons in South Korea. METHODS: A retrospective analysis was conducted of 1265 HIV-1 infected patients who visited four hospitals in South Korea between 1985 and 2012. We analysed the incidence of TB during the follow-up period. To investigate risk factors associated with active TB, we conducted a 1:2 matched case-control study of HIV-infected patients with newly active TB and controls without active TB who had similar CD4(+) T-cell counts and dates of first visit. RESULTS: Over a total of 4457 person-years (py), 185 (14.6%) subjects were diagnosed with active TB; the incidence was 4.2 cases/100 py. In multivariate analysis, low body mass index (P = 0.033) and current smoking (P = 0.003) were independent risk factors for TB in HIV-infected patients. CONCLUSION: Further strategies on prevention and treatment of active TB among HIV-infected patients should be implemented in South Korea. Encouraging smoking cessation and supporting good nutrition may be ways to reduce the incidence of active TB in HIV-infected patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | The Union | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | CD4 Lymphocyte Count | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | HIV Infections/epidemiology* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Smoking/adverse effects | - |
dc.subject.MESH | Smoking/epidemiology* | - |
dc.subject.MESH | Tuberculosis/epidemiology* | - |
dc.subject.MESH | Tuberculosis/etiology | - |
dc.title | Incidence of and risk factors for active tuberculosis in human immunodeficiency virus-infected patients in South Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | Ku, N. S. | - |
dc.contributor.googleauthor | Choi, Y. H. | - |
dc.contributor.googleauthor | Kim, Y. K. | - |
dc.contributor.googleauthor | Choi, J. P. | - |
dc.contributor.googleauthor | Kim, J. M. | - |
dc.contributor.googleauthor | Choi, J. Y. | - |
dc.identifier.doi | 10.5588/ijtld.12.0607 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00189 | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J01167 | - |
dc.identifier.eissn | 1815-7920 | - |
dc.identifier.pmid | 23676161 | - |
dc.identifier.url | http://www.ingentaconnect.com/content/iuatld/ijtld/2013/00000017/00000006/art00013?token=00511fd003c38e7ec150ade67232d45232b45246c7b6f2c6b667323663568293c62207d673f582f6b | - |
dc.subject.keyword | HIV | - |
dc.subject.keyword | TB | - |
dc.subject.keyword | incidence | - |
dc.subject.keyword | risk factors | - |
dc.contributor.alternativeName | Ku, Nam Su | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | Ku, Nam Su | - |
dc.contributor.affiliatedAuthor | Kim, June Myung | - |
dc.contributor.affiliatedAuthor | Choi, Jun Yong | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 17 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 777 | - |
dc.citation.endPage | 781 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Vol.17(6) : 777-781, 2013 | - |
dc.identifier.rimsid | 29222 | - |
dc.type.rims | ART | - |
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