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Is Uterine Artery Embolization for Patients with Large Myomas Safe and Effective? A Retrospective Comparative Study in 323 Patients

Authors
 Hye Jeong Choi  ;  Gyeong Sik Jeon  ;  Man Deuk Kim  ;  Jong Tae Lee  ;  Jung Hyun Yoon 
Citation
 JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, Vol.24(6) : 772-778, 2013 
Journal Title
 JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY 
ISSN
 1051-0443 
Issue Date
2013
MeSH
Adult ; Antineoplastic Agents/therapeutic use* ; Chemoembolization, Therapeutic/statistics & numerical data* ; Female ; Humans ; Middle Aged ; Myoma/epidemiology* ; Myoma/therapy* ; Prevalence ; Republic of Korea/epidemiology ; Retrospective Studies ; Risk Assessment ; Treatment Outcome ; Uterine Artery Embolization/statistics & numerical data* ; Uterine Neoplasms/epidemiology* ; Uterine Neoplasms/therapy* ; Young Adult
Keywords
Adult ; Antineoplastic Agents/therapeutic use* ; Chemoembolization, Therapeutic/statistics & numerical data* ; Female ; Humans ; Middle Aged ; Myoma/epidemiology* ; Myoma/therapy* ; Prevalence ; Republic of Korea/epidemiology ; Retrospective Studies ; Risk Assessment ; Treatment Outcome ; Uterine Artery Embolization/statistics & numerical data* ; Uterine Neoplasms/epidemiology* ; Uterine Neoplasms/therapy* ; Young Adult
Abstract
PURPOSE: To evaluate the effectiveness, safety, and complications of uterine artery embolization (UAE) in women with large fibroid tumors. MATERIALS AND METHODS: From January 2005 to February 2011, 323 patients underwent UAE for symptomatic uterine leiomyomas without adenomyosis and were included in this study. Patients were divided into two groups: those with a large tumor burden (group 1; n = 63), defined as a dominant tumor with a longest axis of at least 10 cm or a uterine volume of at least 700 cm(3); and the control group (group 2; n = 260). Tumor infarction and volume reduction were calculated based on magnetic resonance imaging findings. Symptom status was assessed with a visual analog scale. Postprocedure complications and repeat interventions were recorded. The data were analyzed with appropriate statistical tests. RESULTS: No significant differences were seen between the two groups in volume reduction of dominant tumors (46.5% in group 1 vs 52.0% in group 2; P = .082) or percentage volume reduction of the uterus (40.7% in group 1 vs 36.3% in group 2; P = .114). Also, no significant differences were seen between the two groups regarding satisfaction scores at immediate or midterm follow-up (P = .524 and P = .497) or in the presence of procedure-related complications (P = .193). CONCLUSIONS: UAE outcomes in large fibroid tumors were comparable to those in smaller tumors, without an increased risk of significant complications. Tumor size may not be a key factor in predicting successful outcomes of UAE.
Full Text
http://www.sciencedirect.com/science/article/pii/S1051044313005794
DOI
10.1016/j.jvir.2013.02.003
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Man Deuk(김만득) ORCID logo https://orcid.org/0000-0002-3575-5847
Yoon, Jung Hyun(윤정현) ORCID logo https://orcid.org/0000-0002-2100-3513
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86801
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