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Effects of intermittent lower body perfusion on end-organ function during repair of acute DeBakey type I aortic dissection under moderate hypothermic circulatory arrest

DC Field Value Language
dc.contributor.author송석원-
dc.contributor.author유경종-
dc.date.accessioned2014-12-18T08:38:12Z-
dc.date.available2014-12-18T08:38:12Z-
dc.date.issued2013-
dc.identifier.issn1010-7940-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/86675-
dc.description.abstractOBJECTIVES: To avoid deep hypothermia-related side effects, moderate hypothermic circulatory arrest (HCA) is commonly employed during aortic arch repair, thereby jeopardizing end-organ protection. We sought to analyse the effect of intermittent lower body perfusion (ILBP) on end-organ function during repair of acute DeBakey type I aortic dissection (AIAD). METHODS: Between May 2008 and May 2011, 107 patients underwent surgical repair for AIAD. All operations were performed with selective cerebral perfusion (SCP) under either moderate HCA only (n = 57) or moderate HCA with ILBP (n = 50). Adverse outcomes, including operative mortality, permanent neurological deficit, temporary neurological deficit, renal failure requiring dialysis and hepatic dysfunction, were compared between the two groups. RESULTS: The mean body temperature at the initiation of SCP was 28.7 ± 1.9 °C. Overall operative mortality occurred in 6 (5.6%) patients. The incidences of permanent neurological deficit and temporary neurological deficit were 1.9 and 4.7%, respectively. None of the 9 (8.4%) patients who suffered postoperative renal failure requiring dialysis received ILBP. The laboratory data showed significantly lower levels of hepatic and kidney enzymes in the ILBP group (P < 0.05). CONCLUSIONS: Significantly lower levels of hepatic and kidney enzymes indicate more effective end-organ protection with the use of ILBP. Our data suggest that ILBP provides more effective end-organ protection during repair of aortic arch under moderate HCA.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfEUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAneurysm, Dissecting/surgery*-
dc.subject.MESHAortic Aneurysm/surgery*-
dc.subject.MESHBlood Vessel Prosthesis Implantation-
dc.subject.MESHFemale-
dc.subject.MESHHeart Arrest, Induced/adverse effects-
dc.subject.MESHHeart Arrest, Induced/methods*-
dc.subject.MESHHospital Mortality-
dc.subject.MESHHumans-
dc.subject.MESHHypothermia, Induced/adverse effects-
dc.subject.MESHHypothermia, Induced/methods*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPostoperative Complications/etiology-
dc.subject.MESHReperfusion/adverse effects-
dc.subject.MESHReperfusion/methods-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHTreatment Outcome-
dc.titleEffects of intermittent lower body perfusion on end-organ function during repair of acute DeBakey type I aortic dissection under moderate hypothermic circulatory arrest-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Thoracic & Cardiovascular Surgery (흉부외과학)-
dc.contributor.googleauthorSuk-Won Song-
dc.contributor.googleauthorKyung-Jong Yoo-
dc.contributor.googleauthorYoo Rim Shin-
dc.contributor.googleauthorSun-Hee Lim-
dc.contributor.googleauthorBum-Koo Cho-
dc.identifier.doi10.1093/ejcts/ezt145-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA02028-
dc.contributor.localIdA02453-
dc.relation.journalcodeJ00811-
dc.identifier.eissn1873-734X-
dc.identifier.pmid23509233-
dc.identifier.urlhttp://ejcts.oxfordjournals.org/content/44/6/1070.long-
dc.subject.keywordAortic dissection-
dc.subject.keywordCirculatory arrest-
dc.contributor.alternativeNameSong, Suk Won-
dc.contributor.alternativeNameYoo, Kyung Jong-
dc.contributor.affiliatedAuthorSong, Suk Won-
dc.contributor.affiliatedAuthorYoo, Kyung Jong-
dc.rights.accessRightsnot free-
dc.citation.volume44-
dc.citation.number6-
dc.citation.startPage1070-
dc.citation.endPage1075-
dc.identifier.bibliographicCitationEUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, Vol.44(6) : 1070-1075, 2013-
dc.identifier.rimsid29136-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers

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