7 333

Cited 22 times in

Clinical Characteristics and Prognostic Factors of Primary Pulmonary Vein Stenosis or Atresia in Children

DC FieldValueLanguage
dc.contributor.author김남균-
dc.contributor.author최재영-
dc.date.accessioned2014-12-18T08:36:52Z-
dc.date.available2014-12-18T08:36:52Z-
dc.date.issued2013-
dc.identifier.issn0003-4975-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/86634-
dc.description.abstractBACKGROUND: Primary pulmonary vein stenosis or atresia (PVS/A) is a rare entity with a high mortality rate. The aim of this study was to elucidate the clinical characteristics, progression, and prognostic factors of primary PVS/A in children. METHODS: We reviewed the medical records of patients who had primary PVS/A with normally connected pulmonary veins (PVs) at five pediatric cardiology centers in Korea between 1995 and 2010. RESULTS: A total of 34 cases were identified. The median age at diagnosis was 12.0 months. During the follow-up period (median, 18 months; range, 2 to 185 months), PVS/A progressed to previously uninvolved veins in 9 patients. Surgical interventions were performed on 29 patients (venoplasty on 25 and pneumonectomy on 4). Nineteen of the patients who underwent venoplasty had restenosis after a median of 2 months. The sutureless technique did not reduce the rate of restenosis, progression of the disease to previously uninvolved PVs, or mortality rate. The mortality rate was 46.7%, the median age of death was 10.8 months, and the median interval between diagnosis and death was 3.0 months. In univariate analysis, predictors of death included involvement of at least three PVs, bilateral PV involvement, infancy-onset PVS/A, restenosis after surgery, and progression to previously uninvolved PVs. In multivariate analysis, significant risk factors for death were involvement of at least three PVs (hazard ratio, 8.8; p < 0.0001) and progression to uninvolved PVs (hazard ratio, 4.2; p = 0.014). CONCLUSIONS: Primary PVS/A may carry a significant risk of recurrent and progressive PV obstruction or death even after surgical venoplasty.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfANNALS OF THORACIC SURGERY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHChild, Preschool-
dc.subject.MESHDisease Progression-
dc.subject.MESHFemale-
dc.subject.MESHFollow-Up Studies-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHInfant, Newborn-
dc.subject.MESHMale-
dc.subject.MESHPrognosis-
dc.subject.MESHPulmonary Veins/abnormalities*-
dc.subject.MESHPulmonary Veno-Occlusive Disease/diagnosis*-
dc.subject.MESHPulmonary Veno-Occlusive Disease/mortality-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSeverity of Illness Index-
dc.subject.MESHSurvival Rate/trends-
dc.subject.MESHVascular Malformations/diagnosis*-
dc.subject.MESHVascular Malformations/mortality-
dc.titleClinical Characteristics and Prognostic Factors of Primary Pulmonary Vein Stenosis or Atresia in Children-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthorMi Kyoung Song-
dc.contributor.googleauthorEun Jung Bae-
dc.contributor.googleauthorSoo In Jeong-
dc.contributor.googleauthorI. Seok Kang-
dc.contributor.googleauthorNam Kyun Kim-
dc.contributor.googleauthorJae Young Choi-
dc.contributor.googleauthorSoo Jin Kim-
dc.contributor.googleauthorYoung Hwue Kim-
dc.contributor.googleauthorWoong Han Kim-
dc.identifier.doi10.1016/j.athoracsur.2012.08.104-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04174-
dc.contributor.localIdA00355-
dc.relation.journalcodeJ00183-
dc.identifier.eissn1552-6259-
dc.identifier.pmid23102496-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0003497512020401-
dc.subject.keywordChild, Preschool-
dc.subject.keywordDisease Progression-
dc.subject.keywordFemale-
dc.subject.keywordFollow-Up Studies-
dc.subject.keywordHumans-
dc.subject.keywordInfant-
dc.subject.keywordInfant, Newborn-
dc.subject.keywordMale-
dc.subject.keywordPrognosis-
dc.subject.keywordPulmonary Veins/abnormalities*-
dc.subject.keywordPulmonary Veno-Occlusive Disease/diagnosis*-
dc.subject.keywordPulmonary Veno-Occlusive Disease/mortality-
dc.subject.keywordRepublic of Korea/epidemiology-
dc.subject.keywordRetrospective Studies-
dc.subject.keywordSeverity of Illness Index-
dc.subject.keywordSurvival Rate/trends-
dc.subject.keywordVascular Malformations/diagnosis*-
dc.subject.keywordVascular Malformations/mortality-
dc.contributor.alternativeNameKim, Nam Kyun-
dc.contributor.alternativeNameChoi, Jae Young-
dc.contributor.affiliatedAuthorChoi, Jae Young-
dc.contributor.affiliatedAuthorKim, Nam Kyun-
dc.rights.accessRightsnot free-
dc.citation.volume95-
dc.citation.number1-
dc.citation.startPage229-
dc.citation.endPage235-
dc.identifier.bibliographicCitationANNALS OF THORACIC SURGERY, Vol.95(1) : 229-235, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.