Cited 22 times in
Comparison of meperidine and nefopam for prevention of shivering during spinal anesthesia
DC Field | Value | Language |
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dc.contributor.author | 권태동 | - |
dc.contributor.author | 김명화 | - |
dc.contributor.author | 이기영 | - |
dc.date.accessioned | 2014-12-18T08:36:25Z | - |
dc.date.available | 2014-12-18T08:36:25Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/86620 | - |
dc.description.abstract | BACKGROUND: Shivering is a frequent event during spinal anesthesia and meperidine is a well-known effective drug for prevention and treatment of shivering. Nefopam is a non-opiate analgesic and also known to have an anti-shivering effect. We compared nefopam with meperidine for efficacy of prevention of shivering during spinal anesthesia. METHODS: Sixty five patients, American Society of Anesthesiologists physical status I or II, aged 20-65 years, scheduled for elective orthopedic surgery under spinal anesthesia were investigated. Patients were randomly divided into two groups, meperidine (Group M, n = 33) and nefopam (Group N, n = 32) groups. Group M and N received meperidine 0.4 mg/kg or nefopam 0.15 mg/kg, respectively, in 100 ml of isotonic saline intravenously. All drugs were infused for 15 minutes by a blinded investigator before spinal anesthesia. Blood pressures, heart rates, body temperatures and side effects were checked before and at 15, 30, and 60 minutes after spinal anesthesia. RESULTS: The incidences and scores of shivering were similar between the two groups. The mean arterial pressures in Group N were maintained higher than in Group M at 15, 30, and 60 minutes after spinal anesthesia. The injection pain was checked in Group N only and its incidence was 15.6%. CONCLUSIONS: We conclude that nefopam can be a good substitute for meperidine for prevention of shivering during spinal anesthesia with more stable hemodynamics, if injection pain is effectively controlled. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | KOREAN JOURNAL OF ANESTHESIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Comparison of meperidine and nefopam for prevention of shivering during spinal anesthesia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology (마취통증의학) | - |
dc.contributor.googleauthor | Yeon A Kim | - |
dc.contributor.googleauthor | Tae Dong Kweon | - |
dc.contributor.googleauthor | Myounghwa Kim | - |
dc.contributor.googleauthor | Hye In Lee | - |
dc.contributor.googleauthor | You Jin Lee | - |
dc.contributor.googleauthor | Ki-Young Lee | - |
dc.identifier.doi | 10.4097/kjae.2013.64.3.229 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00255 | - |
dc.contributor.localId | A00429 | - |
dc.contributor.localId | A02695 | - |
dc.relation.journalcode | J01963 | - |
dc.identifier.eissn | 2005-7563 | - |
dc.identifier.pmid | 23560188 | - |
dc.subject.keyword | Meperidine | - |
dc.subject.keyword | Nefopam | - |
dc.subject.keyword | Shivering | - |
dc.subject.keyword | Spinal anesthesia | - |
dc.contributor.alternativeName | Kweon, Tae Dong | - |
dc.contributor.alternativeName | Kim, Myoung Hwa | - |
dc.contributor.alternativeName | Lee, Ki Young | - |
dc.contributor.affiliatedAuthor | Kweon, Tae Dong | - |
dc.contributor.affiliatedAuthor | Kim, Myoung Hwa | - |
dc.contributor.affiliatedAuthor | Lee, Ki Young | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 64 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 229 | - |
dc.citation.endPage | 233 | - |
dc.identifier.bibliographicCitation | KOREAN JOURNAL OF ANESTHESIOLOGY, Vol.64(3) : 229-233, 2013 | - |
dc.identifier.rimsid | 29098 | - |
dc.type.rims | ART | - |
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