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Salicylic Acid Peels Versus Jessner’s Solution for Acne Vulgaris: A Comparative Study

Authors
 Byung Gi Bae  ;  Chang Ook Park  ;  Hyoseung Shin  ;  Soo Hyun Lee  ;  Yun Sun Lee  ;  Sang Ju Lee  ;  Kee Yang Chung  ;  Kwang Hoon Lee  ;  Ju Hee Lee 
Citation
 Dermatologic Surgery, Vol.39(2) : 248-253, 2013 
Journal Title
 Dermatologic Surgery 
ISSN
 1076-0512 
Issue Date
2013
Abstract
BACKGROUND: Salicylic acid was recently formulated in a hydroethanolic vehicle at a concentration of 20% to 30%. Salicylic acid has strong comedolytic effects because of its lipophilic nature. OBJECTIVE: To compare the therapeutic efficacy and tolerability of salicylic acid peels with those of Jessner's solution peels in patients with acne vulgaris. METHODS: Thirteen patients (13 men; mean age 22.6, range 20-28) with facial acne were enrolled. Jessner's solution was applied to one side of each patient's face and 30% salicylic acid to the other in three sessions at 2-week intervals. A blinded investigator counted noninflammatory and inflammatory lesions before treatment and 2 weeks after each treatment. RESULTS: Inflammatory and noninflammatory acne lesion counts decreased in proportion to the duration of treatment. Inflammatory acne lesion counts did not differ significantly between salicylic acid and Jessner's solution peels, although in terms of noninflammatory acne lesion counts, sites treated with salicylic acid showed significant improvement (p = .04), whereas those treated with Jessner's solution did not. CONCLUSION: We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/86413
DOI
10.1111/dsu.12018
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원)
Yonsei Authors
박창욱(Park, Chang Ook) ; 이광훈(Lee, Kwang Hoon) ; 이윤선(Lee, Yun Sun) ; 이주희(Lee, Ju Hee) ; 정기양(Chung, Kee Yang)
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Full Text
http://onlinelibrary.wiley.com/doi/10.1111/dsu.12018/abstract
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