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Random urine protein/creatinine ratio readily predicts proteinuria in preeclampsia
DC Field | Value | Language |
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dc.contributor.author | 권자영 | - |
dc.contributor.author | 김영한 | - |
dc.contributor.author | 박용원 | - |
dc.contributor.author | 손가현 | - |
dc.contributor.author | 조희영 | - |
dc.date.accessioned | 2014-12-18T08:29:11Z | - |
dc.date.available | 2014-12-18T08:29:11Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 2287-8572 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/86397 | - |
dc.description.abstract | OBJECTIVE: To assess the diagnostic accuracy of random urine protein-creatinine (P/C) ratio for prediction of significant proteinuria in preeclampsia as an alternative to the time-consuming 24-hour urine protein collection. METHODS: Retrospective record analysis was performed on 140 pregnant women who were admitted with suspicion for preeclampsia from January 2006 to June 2011. Random urine protein and/or 24-hour urine protein levels were assessed and their correlation to random urine P/C ratio and 24-hour urine protein excretion was evaluated. RESULTS: Out of 140 patients, random urine P/C ratio or/and 24-hour urine protein was performed in 79 patients to evaluate significant proteinuria. Of 79 patients, 46 (58%) underwent both tests whereas in 33 women (42%) 24-hour urine collection was not available due to urgent delivery. In 39 cases (85%), significant proteinuria (≥300 mg/24 hr) was detected with 6 cases (13%) having values over 5,000 mg/24 hr, corresponding to the diagnosis of severe preeclampsia. Random urine P/C ratio highly correlated with 24-hour urine protein excretion (r=0.823, P<0.01). The optimal random urine P/C ratio cutoff points were 0.63 and 4.68 for 300 mg/24 hr and 5,000 mg/24 hr of protein excretion, respectively. with each sensitivity, specificity, and positive and negative predictive values of 87.1%, 100%, 100%, and 58.3%; and 100%, 85%, 50%, and 100%, for significant and severe preeclampsia, respectively. CONCLUSION: Random urine P/C ratio is a reliable indicator of significant proteinuria in preeclampsia and may be better at providing earlier diagnostic information than the 24-hour urine protein excretion with more accuracy than the urinary dipstick test. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | Obstetrics & Gynecology Science | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Random urine protein/creatinine ratio readily predicts proteinuria in preeclampsia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics & Gynecology (산부인과학) | - |
dc.contributor.googleauthor | Jung-Hwa Park | - |
dc.contributor.googleauthor | Dawn Chung | - |
dc.contributor.googleauthor | Hee-Young Cho | - |
dc.contributor.googleauthor | Young-Han Kim | - |
dc.contributor.googleauthor | Ga-Hyun Son | - |
dc.contributor.googleauthor | Yong-Won Park | - |
dc.contributor.googleauthor | Ja-Young Kwon | - |
dc.identifier.doi | 10.5468/OGS.2013.56.1.8 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00246 | - |
dc.contributor.localId | A00730 | - |
dc.contributor.localId | A01581 | - |
dc.contributor.localId | A01963 | - |
dc.contributor.localId | A03944 | - |
dc.relation.journalcode | J02408 | - |
dc.identifier.pmid | 24327974 | - |
dc.subject.keyword | 24-hour urine protein | - |
dc.subject.keyword | Preeclampsia | - |
dc.subject.keyword | Protein-creatinine ratio | - |
dc.contributor.alternativeName | Kwon, Ja Young | - |
dc.contributor.alternativeName | Kim, Young Han | - |
dc.contributor.alternativeName | Park, Yong Won | - |
dc.contributor.alternativeName | Son, Ga Hyun | - |
dc.contributor.alternativeName | Cho, Hee Young | - |
dc.contributor.affiliatedAuthor | Kwon, Ja Young | - |
dc.contributor.affiliatedAuthor | Kim, Young Han | - |
dc.contributor.affiliatedAuthor | Park, Yong Won | - |
dc.contributor.affiliatedAuthor | Son, Ga Hyun | - |
dc.contributor.affiliatedAuthor | Cho, Hee Young | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 56 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 8 | - |
dc.citation.endPage | 14 | - |
dc.identifier.bibliographicCitation | Obstetrics & Gynecology Science, Vol.56(1) : 8-14, 2013 | - |
dc.identifier.rimsid | 28956 | - |
dc.type.rims | ART | - |
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