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Cited 9 times in

Colon carcinoma in childhood: review of the literature with four case reports.

DC FieldValueLanguage
dc.contributor.author허혁-
dc.contributor.author김남규-
dc.contributor.author민병소-
dc.contributor.author백승혁-
dc.contributor.author유철주-
dc.contributor.author이강영-
dc.contributor.author김강미-
dc.date.accessioned2014-12-18T08:29:07Z-
dc.date.available2014-12-18T08:29:07Z-
dc.date.issued2013-
dc.identifier.issn0179-1958-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/86395-
dc.description.abstractPURPOSE: Colorectal cancer (CRC) in childhood is extremely rare, and only a few case reports exist. We hereby present four cases of childhood CRC along with a literature review. METHODS: A retrospective review of four cases from our institute was conducted, and 15 articles from PubMed describing childhood CRC were reviewed. RESULTS: Case reports: Four patients ranging in age from 11 to 14 years were treated for colon cancer between the years 2000 and 2011. The presenting symptoms varied and included abdominal pain, nausea, vomiting, diarrhea, constipation, and hematochezia, with symptom duration ranging from a few days to 4 months. No patient had a predisposing disease or syndrome. All patients underwent surgical resections, with the most prevalent histology being mucinous adenocarcinoma. Despite radical surgery followed by systemic chemotherapy, the disease progressed in all patients. Literature review: A total of 239 cases were reviewed. The youngest patient was 6 years old. The most frequent predisposing conditions were hereditary nonpolyposis colorectal cancer and familial adenomatous polyposis. Most of the patients presented advanced stage, with the most common histopathologic diagnosis being mucinous adenocarcinoma, followed by poorly differentiated adenocarcinoma and signet ring cell carcinoma. Even though most of the patients underwent aggressive treatment, the overall prognosis was poor. CONCLUSIONS: Childhood CRC has an aggressive pathology and distinct genetic features, which result in an advanced stage at diagnosis and consequently a poor prognosis. Although the incidence is very low, every physician should be aware of CRC as a possible childhood diagnosis.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF COLORECTAL DISEASE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHChild-
dc.subject.MESHColonic Neoplasms/pathology*-
dc.subject.MESHColorectal Neoplasms/pathology-
dc.subject.MESHFatal Outcome-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.titleColon carcinoma in childhood: review of the literature with four case reports.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아과학)-
dc.contributor.googleauthorGangmi Kim-
dc.contributor.googleauthorSeung Hyuk Baik-
dc.contributor.googleauthorKang Young Lee-
dc.contributor.googleauthorHyuk Hur-
dc.contributor.googleauthorByung Soh Min-
dc.contributor.googleauthorChuhl Joo Lyu-
dc.contributor.googleauthorNam Kyu Kim-
dc.identifier.doi10.1007/s00384-012-1603-7-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA04373-
dc.contributor.localIdA00353-
dc.contributor.localIdA01402-
dc.contributor.localIdA01827-
dc.contributor.localIdA02524-
dc.contributor.localIdA02640-
dc.relation.journalcodeJ01100-
dc.identifier.eissn1432-1262-
dc.identifier.pmid23099637-
dc.identifier.urlhttp://link.springer.com/article/10.1007%2Fs00384-012-1603-7-
dc.subject.keywordColon carcinoma-
dc.subject.keywordRectal carcinoma-
dc.subject.keywordChildhood-
dc.contributor.alternativeNameHur, Hyuk-
dc.contributor.alternativeNameKim, Nam Kyu-
dc.contributor.alternativeNameMin, Byung Soh-
dc.contributor.alternativeNameBaik, Seung Hyuk-
dc.contributor.alternativeNameLyu, Chuhl Joo-
dc.contributor.alternativeNameLee, Kang Young-
dc.contributor.affiliatedAuthorHur, Hyuk-
dc.contributor.affiliatedAuthorKim, Nam Kyu-
dc.contributor.affiliatedAuthorMin, Byung Soh-
dc.contributor.affiliatedAuthorBaik, Seung Hyuk-
dc.contributor.affiliatedAuthorLyu, Chuhl Joo-
dc.contributor.affiliatedAuthorLee, Kang Young-
dc.rights.accessRightsnot free-
dc.citation.volume28-
dc.citation.number2-
dc.citation.startPage157-
dc.citation.endPage164-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF COLORECTAL DISEASE, Vol.28(2) : 157-164, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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