Cited 37 times in
Comparison of the tuberculin skin test and interferon-γ release assay for the diagnosis of latent tuberculosis infection before kidney transplantation
DC Field | Value | Language |
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dc.contributor.author | 장준 | - |
dc.contributor.author | 정경수 | - |
dc.contributor.author | 주동진 | - |
dc.contributor.author | 강영애 | - |
dc.contributor.author | 김명수 | - |
dc.contributor.author | 김세규 | - |
dc.contributor.author | 김송이 | - |
dc.contributor.author | 김유선 | - |
dc.date.accessioned | 2014-12-18T08:28:11Z | - |
dc.date.available | 2014-12-18T08:28:11Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 0300-8126 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/86365 | - |
dc.description.abstract | PURPOSE: The evaluation of latent tuberculosis infection (LTBI) is recommended before kidney transplantation. The interferon-γ release assay has been reported to be more specific than the tuberculin skin test (TST) for detecting LTBI. We compared the TST and QuantiFERON-TB Gold In-Tube test (QFT-GIT) for the screening for LTBI and determined the agreement between the two tests in renal transplant recipients before transplantation. METHODS: Adult patients who were evaluated for renal transplantation between May 2010 and February 2012 at Severance Hospital in South Korea were prospectively enrolled. We performed TST and QFT-GIT. RESULTS: Of the 126 patients, 23 (19.3 %) had positive TST results and 53 (42.1 %) had positive QFT-GIT results. Agreement between the TST and QFT-GIT was fair (κ = 0.26, P < 0.001). The induration size of TST was significantly correlated with a positive rate of QFT-GIT (P = 0.015). Age (odds ratio [OR] 1.08, 95 % confidence interval [CI] 1.03-1.13, P = 0.003), male sex (OR 2.73, 95 % CI 1.17-6.38, P = 0.021), and risk for LTBI (OR 4.62, 95 % CI 1.15-18.64, P = 0.031) were significantly associated with positive QFT-GIT results. For positive TST results, only male sex was associated (OR 4.29, 95 % CI 1.40-13.20, P = 0.011). CONCLUSION: The positivity for QFT-GIT was higher than the positivity for TST, and QFT-GIT more accurately reflected the risk for LTBI. However, a further longitudinal study is needed in order to confirm that the QFT-GIT test can truly predict the development of TB after renal transplantation. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | INFECTION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Comparison of the tuberculin skin test and interferon-γ release assay for the diagnosis of latent tuberculosis infection before kidney transplantation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학) | - |
dc.contributor.googleauthor | S. Y. Kim | - |
dc.contributor.googleauthor | G. S. Jung | - |
dc.contributor.googleauthor | S. K. Kim | - |
dc.contributor.googleauthor | J. Chang | - |
dc.contributor.googleauthor | M. S. Kim | - |
dc.contributor.googleauthor | Y. S. Kim | - |
dc.contributor.googleauthor | Y. A. Kang | - |
dc.contributor.googleauthor | D. J. Joo | - |
dc.identifier.doi | 10.1007/s15010-012-0291-0 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03472 | - |
dc.contributor.localId | A03570 | - |
dc.contributor.localId | A03948 | - |
dc.contributor.localId | A00057 | - |
dc.contributor.localId | A00602 | - |
dc.contributor.localId | A00626 | - |
dc.contributor.localId | A00785 | - |
dc.contributor.localId | A00424 | - |
dc.relation.journalcode | J01052 | - |
dc.identifier.eissn | 1439-0973 | - |
dc.identifier.pmid | Latent tuberculosis ; Interferon-γ release assay ; Tuberculin skin test ; Kidney transplantation | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs15010-012-0291-0 | - |
dc.subject.keyword | Latent tuberculosis | - |
dc.subject.keyword | Interferon-γ release assay | - |
dc.subject.keyword | Tuberculin skin test | - |
dc.subject.keyword | Kidney transplantation | - |
dc.contributor.alternativeName | Chang, Joon | - |
dc.contributor.alternativeName | Jung, Kyung Soo | - |
dc.contributor.alternativeName | Joo, Dong Jin | - |
dc.contributor.alternativeName | Kang, Young Ae | - |
dc.contributor.alternativeName | Kim, Myoung Soo | - |
dc.contributor.alternativeName | Kim, Se Kyu | - |
dc.contributor.alternativeName | Kim, Song Yi | - |
dc.contributor.alternativeName | Kim, Yu Seun | - |
dc.contributor.affiliatedAuthor | Chang, Joon | - |
dc.contributor.affiliatedAuthor | Jung, Kyung Soo | - |
dc.contributor.affiliatedAuthor | Joo, Dong Jin | - |
dc.contributor.affiliatedAuthor | Kang, Young Ae | - |
dc.contributor.affiliatedAuthor | Kim, Se Kyu | - |
dc.contributor.affiliatedAuthor | Kim, Song Yi | - |
dc.contributor.affiliatedAuthor | Kim, Yu Seun | - |
dc.contributor.affiliatedAuthor | Kim, Myoung Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 41 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 103 | - |
dc.citation.endPage | 110 | - |
dc.identifier.bibliographicCitation | INFECTION, Vol.41(1) : 103-110, 2013 | - |
dc.identifier.rimsid | 28938 | - |
dc.type.rims | ART | - |
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