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Prognostic Factor Analysis in Patients with Metastatic Spine Disease Depending on Surgery and Conservative Treatment: Review of 577 Cases
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김승현 | - |
dc.contributor.author | 조용진 | - |
dc.contributor.author | 김태환 | - |
dc.contributor.author | 김학선 | - |
dc.contributor.author | 문성환 | - |
dc.contributor.author | 문은수 | - |
dc.contributor.author | 박진오 | - |
dc.contributor.author | 이병호 | - |
dc.contributor.author | 이환모 | - |
dc.contributor.author | 김긍년 | - |
dc.contributor.author | 정현수 | - |
dc.date.accessioned | 2014-12-18T08:27:30Z | - |
dc.date.available | 2014-12-18T08:27:30Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1068-9265 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/86344 | - |
dc.description.abstract | Background To date, skillful medical management and advanced surgical techniques have provided increased quality of life with less postoperative morbidity in patients with spinal metastasis. We assessed the survival of patients with spinal metastasis according to two treatment modalities: surgery and conservative treatment. Methods From 2005 to 2010, a total of 577 patients (200 surgery, 377 conservative treatment) who had spinal metastasis were enrolled. Prognostic factors and survival were assessed by Cox regression and Kaplan–Meier analyses in patients receiving either surgery or conservative treatment. Results The mean age was 59.7 (range 21–87) years in the surgery group and 59.9 (range 28–90) years in the conservative treatment group. The major primary cancers were of lung, liver, and colorectal origin in the surgery group and lung, liver, and breast in the conservative group. The mean ± SD Tokuhashi score in the surgery group was 8.12 ± 3.09 and in the conservative group was 8.0 ± 2.8 (not significant). The hazard ratio of the primary cancer group ranged from 1.870 to 3.217 compared to that of the most favorable primary cancer group in all patients. Survival was affected significantly by sex, adjuvant therapy, and postoperative survival in the surgery group and by clinical symptom, metastasis to major internal organ, and primary cancer origin in the conservative group. Conclusions With this retrospective review of 577 cases of spinal metastasis, different prognostic factors depending on the treatment modality were discovered. Hence, consideration of these factors depending on the treatment modality could be helpful in treating patients with spinal metastasis. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | ANNALS OF SURGICAL ONCOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Back Pain/etiology | - |
dc.subject.MESH | Breast/pathology* | - |
dc.subject.MESH | Colorectal Neoplasms/pathology* | - |
dc.subject.MESH | Combined Modality Therapy | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Kaplan-Meier Estimate | - |
dc.subject.MESH | Liver Neoplasms/pathology* | - |
dc.subject.MESH | Lung Neoplasms/pathology* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neck Pain/etiology | - |
dc.subject.MESH | Neoplasm Metastasis | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Radiculopathy/etiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Sex Factors | - |
dc.subject.MESH | Spinal Neoplasms/complications | - |
dc.subject.MESH | Spinal Neoplasms/secondary* | - |
dc.subject.MESH | Spinal Neoplasms/surgery | - |
dc.subject.MESH | Spinal Neoplasms/therapy* | - |
dc.subject.MESH | Young Adult | - |
dc.title | Prognostic Factor Analysis in Patients with Metastatic Spine Disease Depending on Surgery and Conservative Treatment: Review of 577 Cases | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학) | - |
dc.contributor.googleauthor | Byung Ho Lee | - |
dc.contributor.googleauthor | Tae-Hwan Kim | - |
dc.contributor.googleauthor | Hyun-Soo Chong | - |
dc.contributor.googleauthor | Eun-Soo Moon | - |
dc.contributor.googleauthor | Jin-Oh Park | - |
dc.contributor.googleauthor | Hak-Sun Kim | - |
dc.contributor.googleauthor | Seung-Hyun Kim | - |
dc.contributor.googleauthor | Hwan-Mo Lee | - |
dc.contributor.googleauthor | Yong-jin Cho | - |
dc.contributor.googleauthor | Keung Nyun Kim | - |
dc.contributor.googleauthor | Seong-Hwan Moon | - |
dc.identifier.doi | 10.1245/s10434-012-2644-4 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00662 | - |
dc.contributor.localId | A01084 | - |
dc.contributor.localId | A01093 | - |
dc.contributor.localId | A01365 | - |
dc.contributor.localId | A01372 | - |
dc.contributor.localId | A01703 | - |
dc.contributor.localId | A03333 | - |
dc.contributor.localId | A00331 | - |
dc.contributor.localId | A03766 | - |
dc.contributor.localId | A03867 | - |
dc.contributor.localId | A02801 | - |
dc.relation.journalcode | J00179 | - |
dc.identifier.eissn | 1534-4681 | - |
dc.identifier.pmid | 22956070 | - |
dc.identifier.url | http://link.springer.com/article/10.1245/s10434-012-2644-4 | - |
dc.subject.keyword | Primary Cancer | - |
dc.subject.keyword | Spinal Metastasis | - |
dc.subject.keyword | Radicular Pain | - |
dc.subject.keyword | Postoperative Survival | - |
dc.subject.keyword | Conservative Group | - |
dc.contributor.alternativeName | Kim, Seung Hyun | - |
dc.contributor.alternativeName | Cho, Yong Jin | - |
dc.contributor.alternativeName | Kim, Tae Hwan | - |
dc.contributor.alternativeName | Kim, Hak Sun | - |
dc.contributor.alternativeName | Moon, Seong Hwan | - |
dc.contributor.alternativeName | Moon, Eun Su | - |
dc.contributor.alternativeName | Park, Jin Oh | - |
dc.contributor.alternativeName | Lee, Byung Ho | - |
dc.contributor.alternativeName | Lee, Hwan Mo | - |
dc.contributor.alternativeName | Kim, Keung Nyun | - |
dc.contributor.alternativeName | Chong, Hyon Su | - |
dc.contributor.affiliatedAuthor | Kim, Seung Hyun | - |
dc.contributor.affiliatedAuthor | Kim, Tae Hwan | - |
dc.contributor.affiliatedAuthor | Kim, Hak Sun | - |
dc.contributor.affiliatedAuthor | Moon, Seong Hwan | - |
dc.contributor.affiliatedAuthor | Moon, Eun Su | - |
dc.contributor.affiliatedAuthor | Park, Jin Oh | - |
dc.contributor.affiliatedAuthor | Lee, Hwan Mo | - |
dc.contributor.affiliatedAuthor | Kim, Keung Nyun | - |
dc.contributor.affiliatedAuthor | Chong, Hyon Su | - |
dc.contributor.affiliatedAuthor | Cho, Yong Jin | - |
dc.contributor.affiliatedAuthor | Lee, Byung Ho | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 20 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 40 | - |
dc.citation.endPage | 46 | - |
dc.identifier.bibliographicCitation | ANNALS OF SURGICAL ONCOLOGY, Vol.20(1) : 40-46, 2013 | - |
dc.identifier.rimsid | 28925 | - |
dc.type.rims | ART | - |
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