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Clinical Implications and Risk Factors of Acute Pancreatitis after Cardiac Valve Surgery

DC FieldValueLanguage
dc.contributor.author정주원-
dc.contributor.author박승우-
dc.contributor.author박정엽-
dc.contributor.author송시영-
dc.contributor.author이삭-
dc.contributor.author정재복-
dc.date.accessioned2014-12-18T08:23:46Z-
dc.date.available2014-12-18T08:23:46Z-
dc.date.issued2013-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/86226-
dc.description.abstractPURPOSE: Acute pancreatitis is one of the potentially lethal complications that occurs after cardiac surgery. We tried to identify risk factors for and the prognosis of acute pancreatitis after cardiac valve surgery with cardiopulmonary bypass. MATERIALS AND METHODS: We retrospectively analyzed a database of consecutive patients who underwent cardiac valve surgery with cardiopulmonary bypass between January 2005 and April 2010 at our institution. Patients were classified as having acute pancreatitis based on serum lipase concentration and clinical symptoms (lipase ≥ 180 U/L or ≥ 60 U/L with relevant symptoms). RESULTS: Of the 986 patients who underwent cardiac valve surgery with cardiopulmonary bypass, 58 (5.9%) patients developed post-operative pancreatitis. Post-operative hospital stay was significantly longer (29.7 ± 45.6 days vs. 12.4 ± 10.7 days, p = 0.005) and in-hospital mortality rate was higher (15.5% vs. 2.0%, p<0.001) in patients with post-operative pancreatitis than those without. Hypertension, chronic kidney disease, and peri-operative use of norepinephrine were identified as independent risk factors for developing pancreatitis after cardiac valve surgery. CONCLUSION: We found that acute pancreatitis after cardiac valve surgery requires longer hospitalization and increases the in-hospital mortality rate. Clinicians should be aware that patients could develop pancreatitis after cardiac valve surgery, especially in patients with hypertension and chronic kidney disease treated with norepinephrine.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAcute Disease-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCardiac Surgical Procedures/adverse effects-
dc.subject.MESHCardiopulmonary Bypass-
dc.subject.MESHFemale-
dc.subject.MESHHeart Valve Diseases/complications*-
dc.subject.MESHHeart Valve Diseases/surgery*-
dc.subject.MESHHeart Valve Prosthesis Implantation/adverse effects*-
dc.subject.MESHHumans-
dc.subject.MESHLipase/blood-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHNorepinephrine/therapeutic use-
dc.subject.MESHPancreatitis/diagnosis*-
dc.subject.MESHPancreatitis/etiology*-
dc.subject.MESHPostoperative Period-
dc.subject.MESHPrognosis-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Factors-
dc.titleClinical Implications and Risk Factors of Acute Pancreatitis after Cardiac Valve Surgery-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Thoracic & Cardiovascular Surgery (흉부외과학)-
dc.contributor.googleauthorJoo Won Chung-
dc.contributor.googleauthorSung Ho Ryu-
dc.contributor.googleauthorJung Hyun Jo-
dc.contributor.googleauthorJeong Youp Park-
dc.contributor.googleauthorSak Lee-
dc.contributor.googleauthorSeung Woo Park-
dc.contributor.googleauthorSi Young Song-
dc.contributor.googleauthorJae Bock Chung-
dc.identifier.doi10.3349/ymj.2013.54.1.154-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA03726-
dc.contributor.localIdA01551-
dc.contributor.localIdA01647-
dc.contributor.localIdA02035-
dc.contributor.localIdA02807-
dc.contributor.localIdA03706-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid23225812-
dc.subject.keywordAcute pancreatitis-
dc.subject.keywordcardiac valve surgery-
dc.subject.keywordcardiopulmonary bypass-
dc.contributor.alternativeNameChung, Joo Won-
dc.contributor.alternativeNamePark, Seung Woo-
dc.contributor.alternativeNamePark, Jeong Youp-
dc.contributor.alternativeNameSong, Si Young-
dc.contributor.alternativeNameLee, Sak-
dc.contributor.alternativeNameChung, Jae Bock-
dc.contributor.affiliatedAuthorChung, Joo Won-
dc.contributor.affiliatedAuthorPark, Seung Woo-
dc.contributor.affiliatedAuthorPark, Jeong Youp-
dc.contributor.affiliatedAuthorSong, Si Young-
dc.contributor.affiliatedAuthorLee, Sak-
dc.contributor.affiliatedAuthorChung, Jae Bock-
dc.rights.accessRightsfree-
dc.citation.volume54-
dc.citation.number1-
dc.citation.startPage154-
dc.citation.endPage159-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.54(1) : 154-159, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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