Cited 15 times in
Prognostic Usefulness of Eosinopenia in the Pediatric Intensive Care Unit
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경원 | - |
dc.contributor.author | 김규언 | - |
dc.contributor.author | 김민정 | - |
dc.contributor.author | 김윤희 | - |
dc.contributor.author | 김환수 | - |
dc.contributor.author | 박현빈 | - |
dc.contributor.author | 손명현 | - |
dc.contributor.author | 이희선 | - |
dc.contributor.author | 한윤기 | - |
dc.date.accessioned | 2014-12-18T08:21:46Z | - |
dc.date.available | 2014-12-18T08:21:46Z | - |
dc.date.issued | 2013 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/86165 | - |
dc.description.abstract | Eosinopenia, a biomarker for infection, has recently been shown to be a predictor of adult mortality in the intensive care unit (ICU). Our study assessed the usefulness of eosinopenia as a mortality and an infection biomarker in the pediatric ICU (PICU). We compared the PICU mortality scores, eosinophil count and percentage at ICU admission between children who survived and those who did not survive and between children with infection and those without infection. A total of 150 patients were evaluated. The initial eosinophil count and percentage were significantly lower in the group that did not survive when compared to those that did survive (P < 0.001; P < 0.001). However, there was no significant difference in the eosinophil count and percentage seen in patients with and without infection. Eosinopenia, defined as an eosinophil count < 15 cells/µL and an eosinophil percentage < 0.25%, (hazard ratio [HR]: 2.96; P = 0.008) along with a Pediatric Index of Mortality (PIM) 2 (HR: 1.03; P = 0.004) were both determined to be independent predictors of mortality in the PICU. The presence of eosinopenia at the ICU admission can be a useful biomarker for mortality in children, but is not useful as a biomarker for infection. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Agranulocytosis/diagnosis* | - |
dc.subject.MESH | Area Under Curve | - |
dc.subject.MESH | Biomarkers/blood | - |
dc.subject.MESH | Child | - |
dc.subject.MESH | Child, Preschool | - |
dc.subject.MESH | Eosinophils/cytology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hospital Mortality* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Infant | - |
dc.subject.MESH | Infection/mortality | - |
dc.subject.MESH | Infection/pathology | - |
dc.subject.MESH | Intensive Care Units, Pediatric* | - |
dc.subject.MESH | Leukocyte Count | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Predictive Value of Tests | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | ROC Curve | - |
dc.subject.MESH | Survival Rate | - |
dc.title | Prognostic Usefulness of Eosinopenia in the Pediatric Intensive Care Unit | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학) | - |
dc.contributor.googleauthor | Yoon Hee Kim | - |
dc.contributor.googleauthor | Hyun Bin Park | - |
dc.contributor.googleauthor | Min Jung Kim | - |
dc.contributor.googleauthor | Hwan Soo Kim | - |
dc.contributor.googleauthor | Hee Seon Lee | - |
dc.contributor.googleauthor | Yoon Ki Han | - |
dc.contributor.googleauthor | Kyung Won Kim | - |
dc.contributor.googleauthor | Myung Hyun Sohn | - |
dc.contributor.googleauthor | Kyu-Earn Kim | - |
dc.identifier.doi | 10.3346/jkms.2013.28.1.114 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00472 | - |
dc.contributor.localId | A00303 | - |
dc.contributor.localId | A00327 | - |
dc.contributor.localId | A00799 | - |
dc.contributor.localId | A01200 | - |
dc.contributor.localId | A01738 | - |
dc.contributor.localId | A01967 | - |
dc.contributor.localId | A03348 | - |
dc.contributor.localId | A04312 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 23341721 | - |
dc.subject.keyword | Biomarkers | - |
dc.subject.keyword | Child | - |
dc.subject.keyword | Eosinophils | - |
dc.subject.keyword | Infection | - |
dc.subject.keyword | Intensive Care Units | - |
dc.subject.keyword | Prognosis | - |
dc.contributor.alternativeName | Kim, Kyung Won | - |
dc.contributor.alternativeName | Kim, Kyu Earn | - |
dc.contributor.alternativeName | Kim, Min Jung | - |
dc.contributor.alternativeName | Kim, Yoon Hee | - |
dc.contributor.alternativeName | Kim, Hwan Soo | - |
dc.contributor.alternativeName | Park, Hyun Bin | - |
dc.contributor.alternativeName | Son, Myung Hyun | - |
dc.contributor.alternativeName | Lee, Hee Seon | - |
dc.contributor.alternativeName | Han, Yoon Ki | - |
dc.contributor.affiliatedAuthor | Kim, Min Jung | - |
dc.contributor.affiliatedAuthor | Kim, Kyung Won | - |
dc.contributor.affiliatedAuthor | Kim, Kyu Earn | - |
dc.contributor.affiliatedAuthor | Kim, Yoon Hee | - |
dc.contributor.affiliatedAuthor | Kim, Hwan Soo | - |
dc.contributor.affiliatedAuthor | Park, Hyun Bin | - |
dc.contributor.affiliatedAuthor | Son, Myung Hyun | - |
dc.contributor.affiliatedAuthor | Lee, Hee Seon | - |
dc.contributor.affiliatedAuthor | Han, Yoon Ki | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 28 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 114 | - |
dc.citation.endPage | 119 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.28(1) : 114-119, 2013 | - |
dc.identifier.rimsid | 28825 | - |
dc.type.rims | ART | - |
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