소아 횡문근육종의 치료 결과

Abstract

Rhabdomyosarcoma is a relatively common solid tumor in infants, children and adolescents, according for 4% to 8% of malignant disease in children less than 15 years old. Use of a multimodal approach to treatment has resulted in a dramatic improvement. Yonsei Cancer Center in Korea, since it's establishment in 1975, has been a state of multimodal approach. Thirty-seven cases of childhood rhabdomyosarcoma registered and followed-up at Yonsei Cancer Center, between Januay 1980 and December 1989 were analysed retrospectively. All patients were assigned to one of four clinical groups on the basis of extent of disease. The number of cases for Group I, II, III and IV was 3(8%), 7(19%), 21(57%) and 6(16%) respectively. There were relatively small number of cases with total tumor removel (Group I and II). Among the registered patients, there were cases of no proper treated after diagnosed. The results of treatment as follows: three year survival rate for Group I, II and III was 67%, 43% and 48% respectively. Two year survival rate for Group IV was 17% but none was survived at three year of follow-up period. There were seventeen registered patients who were completely treated by recommended therapeutic plans. Three year survival rate of this patients by Group I, II and III was 100% (2 patients), 67% and 73% respectively.