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The Asian Pacific association for the study of the liver clinical practice guidelines for the diagnosis and management of metabolic dysfunction-associated fatty liver disease

Authors
 Eslam, Mohammed  ;  Fan, Jian-Gao  ;  Yu, Ming-Lung  ;  Wong, Vincent Wai-Sun  ;  Cua, Ian Homer  ;  Liu, Chun-Jen  ;  Tanwandee, Tawesak  ;  Gani, Rino  ;  Seto, Wai-Kay  ;  Alam, Shahinul  ;  Young, Dan Yock  ;  Hamid, Saeed  ;  Zheng, Ming-Hua  ;  Kawaguchi, Takumi  ;  Chan, Wah-Kheong  ;  Payawal, Diana  ;  Tan, Soek-Siam  ;  Goh, George Boon-bee  ;  Strasser, Simone I.  ;  Viet, Hang Dao  ;  Kao, Jia-Horng  ;  Kim, Won  ;  Kim, Seung Up  ;  Keating, Shelley E.  ;  Yilmaz, Yusuf  ;  Kamani, Lubna  ;  Wang, Chia-Chi  ;  Fouad, Yasser  ;  Abbas, Zaigham  ;  Treeprasertsuk, Sombat  ;  Thanapirom, Kessarin  ;  Al Mahtab, Mamun  ;  Lkhagvaa, Undram  ;  Baatarkhuu, Oidov  ;  Choudhury, Ashok Kumar  ;  Stedman, Catherine A. M.  ;  Chowdhury, Abhijit  ;  Dokmeci, A. Kadir  ;  Wang, Fu-Sheng  ;  Lin, Han-Chieh  ;  Huang, Jee-Fu  ;  Howell, Jess  ;  Jia, Jidong  ;  Alboraie, Mohamed  ;  Roberts, Stuart K.  ;  Yoneda, Masato  ;  Ghazinian, Hasmik  ;  Mirijanyan, Aram  ;  Nan, Yuemin  ;  Lesmana, Cosmas Rinaldi Adithya  ;  Adams, Leon A.  ;  Shiha, Gamal  ;  Kumar, Manoj  ;  Oermeci, Necati  ;  Wei, Lai  ;  Lau, George  ;  Omata, Masao  ;  Sarin, Shiv K.  ;  George, Jacob 
Citation
 HEPATOLOGY INTERNATIONAL, Vol.19(2) : 261-301, 2025-04 
Article Number
 e070189 
Journal Title
HEPATOLOGY INTERNATIONAL
ISSN
 1936-0533 
Issue Date
2025-04
MeSH
Fatty Liver* / diagnosis ; Fatty Liver* / epidemiology ; Fatty Liver* / therapy ; Humans ; Non-alcoholic Fatty Liver Disease* / diagnosis ; Non-alcoholic Fatty Liver Disease* / epidemiology ; Non-alcoholic Fatty Liver Disease* / therapy
Keywords
Alanine Aminotransferase ; Alpha 2 Macroglobulin ; Hyaluronic Acid ; Alanine Aminotransferase ; Alpha 2 Macroglobulin ; High Density Lipoprotein Cholesterol ; Hyaluronic Acid ; Advanced Fibrosis ; Aerobic Exercise ; Article ; Artificial Intelligence ; Bariatric Surgery ; Cardiorespiratory Fitness ; Cardiovascular Disease ; Chronic Kidney Failure ; Chronic Obstructive Lung Disease ; Clinical Assessment ; Clinical Practice ; Clinical Practice Guideline ; Controlled Study ; Decision Making ; Diagnostic Accuracy ; Diagnostic Test Accuracy Study ; Disease Severity ; Dyslipidemia ; Echography ; Evidence Based Practice ; False Negative Result ; Fibrosis ; Gastroplasty ; Health Care ; Health Care Cost ; Human ; Hypertension ; Hypogonadism ; Hypothyroidism ; Inflammation ; Insulin Sensitivity ; Ischemic Stroke ; Limit Of Quantitation ; Liver ; Liver Biopsy ; Liver Disease ; Magnetic Resonance Elastography ; Meta Analysis (topic) ; Metabolic Fatty Liver ; Multidisciplinary Team ; Non Insulin Dependent Diabetes Mellitus ; Nonalcoholic Steatohepatitis ; Obesity ; Obstructive Sleep Apnea ; Ovary Polycystic Disease ; Peptic Ulcer Bleeding ; Portal Hypertension ; Predictive Value ; Prevalence ; Quality Of Life ; Randomized Controlled Trial ; Roux-en-y Gastric Bypass ; Sarcopenia ; Scoring System ; Screening ; Sensitivity And Specificity ; Sleeve Gastrectomy ; Transient Elastography ; Diagnosis ; Epidemiology ; Fatty Liver ; Nonalcoholic Fatty Liver ; Practice Guideline ; Therapy ; Fatty Liver ; Humans ; Non-alcoholic Fatty Liver Disease
Abstract
Metabolic dysfunction-associated fatty liver disease (MAFLD) affects over one-fourth of the global adult population and is the leading cause of liver disease worldwide. To address this, the Asian Pacific Association for the Study of the Liver (APASL) has created clinical practice guidelines focused on MAFLD. The guidelines cover various aspects of the disease, such as its epidemiology, diagnosis, screening, assessment, and treatment. The guidelines aim to advance clinical practice, knowledge, and research on MAFLD, particularly in special groups. The guidelines are designed to advance clinical practice, to provide evidence-based recommendations to assist healthcare stakeholders in decision-making and to improve patient care and disease awareness. The guidelines take into account the burden of clinical management for the healthcare sector.
Full Text
https://link.springer.com/article/10.1007/s12072-024-10774-3
DOI
10.1007/s12072-024-10774-3
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Seung Up(김승업) ORCID logo https://orcid.org/0000-0002-9658-8050
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/208662
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