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Effectiveness of single-pill combination olmesartan/amlodipine/hydrochlorothiazide therapy in patients with apparent resistant hypertension

DC Field Value Language
dc.contributor.authorOh, Jaewon-
dc.contributor.authorKim, Wonho-
dc.contributor.authorKim, Gee-Hee-
dc.contributor.authorKim, Hack-Lyoung-
dc.contributor.authorPark, Sang-Don-
dc.contributor.authorMin, Kyung Wan-
dc.contributor.authorHyun, Dongkeun-
dc.contributor.authorHong, Jun Hwa-
dc.contributor.authorLim, Soo-
dc.contributor.authorBae, Ji-Hwan-
dc.contributor.authorShin, Jinho-
dc.date.accessioned2025-10-27T02:53:28Z-
dc.date.available2025-10-27T02:53:28Z-
dc.date.created2025-09-22-
dc.date.issued2025-09-
dc.identifier.issn0950-9240-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/207957-
dc.description.abstractThis pioneering study investigated the real-life effectiveness of single-pill combination (SPC) antihypertensive therapy in patients with uncontrolled blood pressure (BP) and cardiovascular risk factors. After treatment with olmesartan medoxomil/amlodipine besylate/hydrochlorothiazide for 24 weeks, adults with apparent resistant hypertension had significantly reduced systolic BP and approximately 80% achieved target BP. SPC therapy may improve adherence in patients with pseudo-resistant hypertension and is a potentially effective treatment for resistant hypertension.-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfJOURNAL OF HUMAN HYPERTENSION-
dc.relation.isPartOfJOURNAL OF HUMAN HYPERTENSION-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAmlodipine* / administration & dosage-
dc.subject.MESHAmlodipine* / adverse effects-
dc.subject.MESHAmlodipine* / therapeutic use-
dc.subject.MESHAntihypertensive Agents* / administration & dosage-
dc.subject.MESHAntihypertensive Agents* / adverse effects-
dc.subject.MESHAntihypertensive Agents* / therapeutic use-
dc.subject.MESHBlood Pressure* / drug effects-
dc.subject.MESHDrug Combinations-
dc.subject.MESHDrug Resistance-
dc.subject.MESHDrug Therapy, Combination-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHHydrochlorothiazide* / administration & dosage-
dc.subject.MESHHydrochlorothiazide* / adverse effects-
dc.subject.MESHHydrochlorothiazide* / therapeutic use-
dc.subject.MESHHypertension* / diagnosis-
dc.subject.MESHHypertension* / drug therapy-
dc.subject.MESHHypertension* / physiopathology-
dc.subject.MESHImidazoles* / administration & dosage-
dc.subject.MESHImidazoles* / therapeutic use-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOlmesartan Medoxomil-
dc.subject.MESHTetrazoles* / administration & dosage-
dc.subject.MESHTetrazoles* / therapeutic use-
dc.subject.MESHTreatment Outcome-
dc.titleEffectiveness of single-pill combination olmesartan/amlodipine/hydrochlorothiazide therapy in patients with apparent resistant hypertension-
dc.typeArticle-
dc.contributor.googleauthorOh, Jaewon-
dc.contributor.googleauthorKim, Wonho-
dc.contributor.googleauthorKim, Gee-Hee-
dc.contributor.googleauthorKim, Hack-Lyoung-
dc.contributor.googleauthorPark, Sang-Don-
dc.contributor.googleauthorMin, Kyung Wan-
dc.contributor.googleauthorHyun, Dongkeun-
dc.contributor.googleauthorHong, Jun Hwa-
dc.contributor.googleauthorLim, Soo-
dc.contributor.googleauthorBae, Ji-Hwan-
dc.contributor.googleauthorShin, Jinho-
dc.identifier.doi10.1038/s41371-025-01043-3-
dc.relation.journalcodeJ01447-
dc.identifier.eissn1476-5527-
dc.identifier.pmid40659924-
dc.contributor.affiliatedAuthorOh, Jaewon-
dc.identifier.scopusid2-s2.0-105015807235-
dc.identifier.wosid001528208900001-
dc.citation.volume39-
dc.citation.number9-
dc.citation.startPage675-
dc.citation.endPage678-
dc.identifier.bibliographicCitationJOURNAL OF HUMAN HYPERTENSION, Vol.39(9) : 675-678, 2025-09-
dc.identifier.rimsid89554-
dc.type.rimsART-
dc.description.journalClass1-
dc.description.journalClass1-
dc.type.docTypeArticle; Early Access-
dc.description.isOpenAccessY-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
dc.relation.journalWebOfScienceCategoryPeripheral Vascular Disease-
dc.relation.journalResearchAreaCardiovascular System & Cardiology-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
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