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Intravascular Ultrasound Predictors of 12-Month Patency Loss Following Drug-Coated Balloon Angioplasty for the Femoropopliteal Artery

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dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author김중선-
dc.contributor.author안철민-
dc.contributor.author이상협-
dc.contributor.author이승준-
dc.contributor.author임의-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.contributor.author홍성진-
dc.date.accessioned2025-10-15T01:58:28Z-
dc.date.available2025-10-15T01:58:28Z-
dc.date.issued2025-07-
dc.identifier.issn0002-9149-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/207533-
dc.description.abstractangioplasty ; drug-coated balloon ; femoropopliteal artery ; intravascular ultrasound ; peripheral artery disease-
dc.description.statementOfResponsibilityhttps://www.sciencedirect.com/science/article/pii/S0002914925001742-
dc.languageEnglish-
dc.publisherExcerpta Medica-
dc.relation.isPartOfAMERICAN JOURNAL OF CARDIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESH1-
dc.titleIntravascular Ultrasound Predictors of 12-Month Patency Loss Following Drug-Coated Balloon Angioplasty for the Femoropopliteal Artery-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJaeoh Lee-
dc.contributor.googleauthorJi Yong Jang-
dc.contributor.googleauthorChul-Min Ahn-
dc.contributor.googleauthorSeung-Jun Lee-
dc.contributor.googleauthorSang-Hyup Lee-
dc.contributor.googleauthorYong-Joon Lee-
dc.contributor.googleauthorSung-Jin Hong-
dc.contributor.googleauthorJung-Sun Kim-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorTae-Hoon Kim-
dc.contributor.googleauthorHa-Wook Park-
dc.contributor.googleauthorJae-Hwan Lee-
dc.contributor.googleauthorJae-Hyeong Park-
dc.contributor.googleauthorSu Hong Kim-
dc.contributor.googleauthorEui Im-
dc.contributor.googleauthorSang-Ho Park-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorIVUS-DCB Investigators-
dc.identifier.doiIntravascular ultrasound (IVUS) has been shown to improve outcomes of drug-coated balloon (DCB) angioplasty for treatment of femoropopliteal artery (FPA) disease. However, the optimal IVUS criteria for achieving improved outcomes of DCB angioplasty for FPA disease remain uncertain. The study aimed to identify IVUS predictors for loss of patency at 12 months after DCB angioplasty for FPA disease. After excluding one patient due to insufficient IVUS imaging data, 98 patients in the IVUS-guidance group of the IVUS-DCB trial were included in the analysis. IVUS parameters predicting loss of patency at 12 months and their optimal cut-off values were investigated. Among the 98 patients who underwent IVUS-guided FPA intervention, 16 patients (16.3%) lost primary patency within 12 months. End-stage renal disease on hemodialysis and, bailout stenting, postprocedural dissection length >50% were independent procedural predictors for 12-month patency loss. Receiver operating characteristic (ROC) curve demonstrated that postprocedural minimal lumen area (MLA) ≥ 11.6 mm2 (area under the ROC curve: 0.685, 95% CI: 0.513 to 0.857) as the optimal cut-off value for sustained primary patency. In survival analysis, patients with MLA ≥ 11.6 mm2 had a hazard ratio of 0.27 (95% CI: 0.09 to 0.80, p-value = 0.019, risk difference: 19.8) for lower risk of patency loss. A postprocedural MLA ≥11.6 mm2 was an independent IVUS predictor for sustained primary patency after DCB angioplasty in patients with FPA disease. Our findings suggest that lesion optimization and achieving sufficient lumen area under IVUS guidance during DCB angioplasty are crucial for maintaining target vessel patency.-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA00961-
dc.contributor.localIdA02269-
dc.contributor.localIdA06152-
dc.contributor.localIdA02927-
dc.contributor.localIdA03394-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.contributor.localIdA04403-
dc.relation.journalcodeJ00071-
dc.identifier.eissn1879-1913 -
dc.identifier.pmid40154590-
dc.subject.keywordAged-
dc.subject.keywordAngioplasty, Balloon* / methods-
dc.subject.keywordCoated Materials, Biocompatible*-
dc.subject.keywordFemale-
dc.subject.keywordFemoral Artery* / diagnostic imaging-
dc.subject.keywordFemoral Artery* / surgery-
dc.subject.keywordFollow-Up Studies-
dc.subject.keywordHumans-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordPeripheral Arterial Disease* / diagnostic imaging-
dc.subject.keywordPeripheral Arterial Disease* / surgery-
dc.subject.keywordPeripheral Arterial Disease* / therapy-
dc.subject.keywordPopliteal Artery* / diagnostic imaging-
dc.subject.keywordPopliteal Artery* / surgery-
dc.subject.keywordROC Curve-
dc.subject.keywordRetrospective Studies-
dc.subject.keywordTime Factors-
dc.subject.keywordTreatment Outcome-
dc.subject.keywordUltrasonography, Interventional* / methods-
dc.subject.keywordVascular Patency* / physiology-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.affiliatedAuthor고영국-
dc.contributor.affiliatedAuthor김병극-
dc.contributor.affiliatedAuthor김중선-
dc.contributor.affiliatedAuthor안철민-
dc.contributor.affiliatedAuthor이상협-
dc.contributor.affiliatedAuthor이승준-
dc.contributor.affiliatedAuthor임의-
dc.contributor.affiliatedAuthor장양수-
dc.contributor.affiliatedAuthor최동훈-
dc.contributor.affiliatedAuthor홍명기-
dc.contributor.affiliatedAuthor홍성진-
dc.citation.volume246-
dc.citation.startPage58-
dc.citation.endPage64-
dc.identifier.bibliographicCitationAMERICAN JOURNAL OF CARDIOLOGY, Vol.246 : 58-64, 2025-07-
dc.identifier.articleno10.1016/j.amjcard.2025.03.018-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
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