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Twenty-Four-Month Outcomes of Intravascular Ultrasound-Guided Drug-Coated Balloon Angioplasty for Femoropopliteal Artery Disease

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dc.contributor.author고영국-
dc.contributor.author김병극-
dc.contributor.author안철민-
dc.contributor.author이상협-
dc.contributor.author이승준-
dc.contributor.author임의-
dc.contributor.author장양수-
dc.contributor.author최동훈-
dc.contributor.author홍명기-
dc.date.accessioned2025-10-15T01:57:20Z-
dc.date.available2025-10-15T01:57:20Z-
dc.date.issued2025-08-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/207529-
dc.description.abstractdrug‐coated balloon ; femoropopliteal artery disease ; imaging‐guided angioplasty ; intravascular ultrasound ; peripheral artery disease-
dc.description.statementOfResponsibilityT202506229.pdf-
dc.languageEnglish-
dc.publisherWiley-Blackwell-
dc.relation.isPartOfJOURNAL OF THE AMERICAN HEART ASSOCIATION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESH0-
dc.titleTwenty-Four-Month Outcomes of Intravascular Ultrasound-Guided Drug-Coated Balloon Angioplasty for Femoropopliteal Artery Disease-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJonghu Shin-
dc.contributor.googleauthorChul-Min Ahn-
dc.contributor.googleauthorSeung-Jun Lee-
dc.contributor.googleauthorSang-Hyup Lee-
dc.contributor.googleauthorYong-Joon Lee-
dc.contributor.googleauthorByeong-Keuk Kim-
dc.contributor.googleauthorMyeong-Ki Hong-
dc.contributor.googleauthorYangsoo Jang-
dc.contributor.googleauthorTae-Hoon Kim-
dc.contributor.googleauthorHa-Wook Park-
dc.contributor.googleauthorJi Yong Jang-
dc.contributor.googleauthorJae-Hwan Lee-
dc.contributor.googleauthorJae-Hyeong Park-
dc.contributor.googleauthorSu Hong Kim-
dc.contributor.googleauthorEui Im-
dc.contributor.googleauthorSang-Ho Park-
dc.contributor.googleauthorDonghoon Choi-
dc.contributor.googleauthorYoung-Guk Ko-
dc.contributor.googleauthorIVUS‐DCB investigators-
dc.identifier.doiBackground: The IVUS-DCB (Intravascular Ultrasound-Guided Drug-Coated Balloon Angioplasty for Femoropopliteal Artery Disease) trial found that intravascular ultrasound (IVUS)-guided drug-coated balloon (DCB) angioplasty was associated with superior 12-month outcomes, compared with conventional angiography-guided DCB angioplasty. However, the durability of these benefits remains uncertain. The aim of this study was to compare the 24-month outcomes of IVUS-guided versus angiography-guided DCB angioplasty for femoropopliteal artery disease. Methods: This extended study analyzed a total of 237 patients who were previously randomized into IVUS-guidance (n=119) or angiography-guidance (n=118) groups in the original IVUS-DCB trial. The 24-month clinical efficacy outcomes included freedom from clinically driven target lesion revascularization, sustained clinical and hemodynamic improvements, and freedom from major amputation. Results: At 24-month follow-up, the IVUS-guidance group exhibited significantly higher rates of freedom from clinically driven target lesion revascularization (87.4% versus 78.0%; hazard ratio, 0.46 [95% CI, 0.24-0.88]; P=0.02), sustained clinical improvement (82.4% versus 71.2%, P=0.02), and sustained hemodynamic improvement (74.8% versus 61.0%, P=0.01), compared with the angiography-guidance group. No major amputations occurred in either group during the 24-month follow-up. There were no significant differences in safety outcomes between groups, including all-cause death, cardiovascular death, and major bleeding. Conclusions: At 24-month follow-up, IVUS-guided DCB angioplasty for femoropopliteal artery disease continued to demonstrate superior outcomes, compared with angiography-guided DCB angioplasty, in terms of freedom from clinically driven target lesion revascularization, sustained clinical improvement, and sustained hemodynamic improvement.-
dc.contributor.localIdA00127-
dc.contributor.localIdA00493-
dc.contributor.localIdA02269-
dc.contributor.localIdA06152-
dc.contributor.localIdA02927-
dc.contributor.localIdA03394-
dc.contributor.localIdA03448-
dc.contributor.localIdA04053-
dc.contributor.localIdA04391-
dc.relation.journalcodeJ01774-
dc.identifier.eissn2047-9980-
dc.identifier.pmid40792582-
dc.subject.keywordAged-
dc.subject.keywordAmputation, Surgical-
dc.subject.keywordAngiography-
dc.subject.keywordAngioplasty, Balloon* / adverse effects-
dc.subject.keywordAngioplasty, Balloon* / instrumentation-
dc.subject.keywordAngioplasty, Balloon* / methods-
dc.subject.keywordCoated Materials, Biocompatible*-
dc.subject.keywordFemale-
dc.subject.keywordFemoral Artery* / diagnostic imaging-
dc.subject.keywordFemoral Artery* / physiopathology-
dc.subject.keywordFollow-Up Studies-
dc.subject.keywordHumans-
dc.subject.keywordLimb Salvage-
dc.subject.keywordMale-
dc.subject.keywordMiddle Aged-
dc.subject.keywordPeripheral Arterial Disease* / diagnostic imaging-
dc.subject.keywordPeripheral Arterial Disease* / physiopathology-
dc.subject.keywordPeripheral Arterial Disease* / therapy-
dc.subject.keywordPopliteal Artery* / diagnostic imaging-
dc.subject.keywordPopliteal Artery* / physiopathology-
dc.subject.keywordTime Factors-
dc.subject.keywordTreatment Outcome-
dc.subject.keywordUltrasonography, Interventional*-
dc.subject.keywordVascular Access Devices*-
dc.subject.keywordVascular Patency-
dc.contributor.alternativeNameKo, Young Guk-
dc.contributor.affiliatedAuthor고영국-
dc.contributor.affiliatedAuthor김병극-
dc.contributor.affiliatedAuthor안철민-
dc.contributor.affiliatedAuthor이상협-
dc.contributor.affiliatedAuthor이승준-
dc.contributor.affiliatedAuthor임의-
dc.contributor.affiliatedAuthor장양수-
dc.contributor.affiliatedAuthor최동훈-
dc.contributor.affiliatedAuthor홍명기-
dc.citation.volume14-
dc.citation.number16-
dc.citation.startPagee041564-
dc.identifier.bibliographicCitationJOURNAL OF THE AMERICAN HEART ASSOCIATION, Vol.14(16) : e041564, 2025-08-
dc.identifier.articleno10.1161/JAHA.125.041564-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
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