류코트리엔 조절제를 사용중인 기관지천식 환자에서 경구 부신피질 호르몬 감량후 발병한 Churg-Strauss 증후군 1례

Abstract

Churg-Strauss syndrome is one of idiopathic, systemic necrotizing vasculitis characterized by a history of asthma or allergic rhinitis, eosinophilia of peripheral blood and variable symptoms of systemic vasculitis. There have been several recent case reports of Churg-Strauss syndrome in association with leukotriene modifier therapy when oral corticosteroids were withdrawn in asthmatic patients. We report a case of a 31-year-old man with steroid-dependent asthma who developed Churg-Strauss syndrome after 9 months of steroid withdrawal period, while he was receiving leukotriene modifier (Pranlukast).