특발성 혈소판 감소성 자반병과 동반된 중증 근무력증 1예

Abstract

Myasthenia gravis has been associated with a variety of autoimmune diseases, but the association of myasthenia gravis with idiopathic thrombocytopenic purpura has been rarely reported. A previously healthy 33-year-old female presented with a 10-month history of easy fatigability, motor weakness, diplopia and menorrhage. Clinical and labora tory findings supported the diagnosis of myasthenia gravis and idiopathic thrombocytopenic purpura. After a thymecto my, there were surprising improvements not only in muscle strength, but also of thrombocytopenia. Though this associ ation may be incidental, the patient’s progress suggests that idiopathic thrombocytopenic purpura may be closely relat ed to myasthenia gravis immunologically because both diseases developed simultaneously and showed good therapeu tic responses after a thymectomy.