Congenitally corrected transposition of the great arteries: one disease, diverse manifestations-a case series

Abstract

Background: Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital heart defect with heterogenous clinical manifestations that can pose both diagnostic and management challenges throughout life.

Case summary: We describe four patients with ccTGA and different presentations including sudden cardiac arrest, progressive heart failure, post-partum heart failure, and NSTEMI.

Aims and discussion: This case series aims to illustrate the importance of multimodality imaging to assist the diagnosis and support treatment strategies in patients with ccTGA. Direct long-term sequalae, such as arrythmias and heart failure, and the associated management challenges are highlighted. Additionally, the challenges of managing pregnancy with a sRV and the development of acquired heart disease demonstrate the clinical care challenges in caring for this population across the life span.