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One-year mortality and morbidities of severe fever with thrombocytopenia syndrome compared with other diseases: A nationwide cohort study in South Korea
DC Field | Value | Language |
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dc.contributor.author | 김용찬 | - |
dc.contributor.author | 박윤수 | - |
dc.date.accessioned | 2024-07-18T05:29:33Z | - |
dc.date.available | 2024-07-18T05:29:33Z | - |
dc.date.issued | 2024-06 | - |
dc.identifier.issn | 1935-2727 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/200104 | - |
dc.description.abstract | Background: The long-term mortality and morbidity of patients with severe fever with thrombocytopenia syndrome (SFTS) remain unclear. Methods: This retrospective cohort study was conducted using the National Health Insurance Service dataset on hospitalized patients with SFTS aged ≥20 years between 2016 and 2021 (n = 1,217). Each SFTS case was matched with three controls hospitalized for non-SFTS-related diseases using propensity score matching. The all-cause mortality of patients with SFTS was evaluated during the one-year follow-up and compared with that of controls. Post-discharge events were investigated to determine the effects of SFTS on post-acute sequelae. Results: Finally, 1,105 patients with SFTS and 3,315 controls were included. Patients with SFTS had a higher risk of death during the one-year follow-up than that of controls (hazard ratio [HR], 2·26; 95% confidence interval [CI], 1·82-2·81). Thirty-day mortality was significantly higher in the SFTS group (HR, 3·99; 95% CI, 3·07-5·19) than in the control group. An increased risk of death after 31-365 days was observed among controls, though this difference was significant only among patients in their 80s (HR, 0·18; 95% CI, 0·06-0·57). For post-discharge events, patients in the SFTS group exhibited a higher risk of readmission (HR, 1·17; 95% CI, 1·04-1·32) and emergency room visit (HR, 2·32; 95% CI, 1·96-2·76) than those in the control group. Conclusion: SFTS induces a higher risk of short-term mortality and post-acute sequelae in hospitalized patients during a one-year follow-up than non-SFTS-related diseases. Our results provide guidance for the management of SFTS. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Public Library of Science | - |
dc.relation.isPartOf | PLOS NEGLECTED TROPICAL DISEASES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hospitalization / statistics & numerical data | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Morbidity | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Severe Fever with Thrombocytopenia Syndrome* / epidemiology | - |
dc.subject.MESH | Severe Fever with Thrombocytopenia Syndrome* / mortality | - |
dc.subject.MESH | Young Adult | - |
dc.title | One-year mortality and morbidities of severe fever with thrombocytopenia syndrome compared with other diseases: A nationwide cohort study in South Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Namwoo Heo | - |
dc.contributor.googleauthor | Seok-Jae Heo | - |
dc.contributor.googleauthor | Yoon Soo Park | - |
dc.contributor.googleauthor | Seonju Yi | - |
dc.contributor.googleauthor | Hyunju Lee | - |
dc.contributor.googleauthor | Hyo-Jung Lee | - |
dc.contributor.googleauthor | Yong Chan Kim | - |
dc.identifier.doi | 10.1371/ journal.pntd.0012253 | - |
dc.contributor.localId | A00752 | - |
dc.contributor.localId | A01598 | - |
dc.relation.journalcode | J03099 | - |
dc.identifier.eissn | 1935-2735 | - |
dc.identifier.pmid | 38875294 | - |
dc.contributor.alternativeName | Kim, Yong Chan | - |
dc.contributor.affiliatedAuthor | 김용찬 | - |
dc.contributor.affiliatedAuthor | 박윤수 | - |
dc.citation.volume | 18 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | e0012253 | - |
dc.identifier.bibliographicCitation | PLOS NEGLECTED TROPICAL DISEASES, Vol.18(6) : e0012253, 2024-06 | - |
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