Cited 0 times in
Sex differences in the global burden of multidrug- resistant tuberculosis without extensive drug resistance in the general population and people living with HIV/AIDS, 1990-2019
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 신재일 | - |
dc.date.accessioned | 2024-07-18T05:23:07Z | - |
dc.date.available | 2024-07-18T05:23:07Z | - |
dc.date.issued | 2024-05 | - |
dc.identifier.issn | 1128-3602 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/200079 | - |
dc.description.abstract | OBJECTIVE: Currently, human immunodeficiency virus (HIV) and multi-drug resistant tuberculosis (MDR-TB) without extensive drug resistance (XDR) are significant challenges in terms of the global burden of disease. This study aimed to evaluate the trends of the global burden of MDR-TB without XDR and HIV/AIDS-MDR-TB without XDR, focusing on differences in socioeconomic status and sex for 204 countries and territories across periods from 1990 to 2019. MATERIALS AND METHODS: Data from the Global Burden of Disease (GBD) 2019 study were obtained to construct a separate index measuring the burden of MDR-TB without XDR and HIV/AIDS-MDR-TB without XDR. Incidence, prevalence, mortality, and disability-adjusted life years (DALYs) were calculated for each case and group. A population-attributable fraction approach was used to assess mortality and incidence of HIV/AIDS and MDR-TB coinfection. 95% uncertainty intervals (UIs) were presented for all measures. RESULTS: Our global estimates suggest that there were approximately 450,000 (95% UI 247,000-785,000) incident cases of MDR-TB without XDR and 109,000 (43,000-210,000) deaths caused by MDR-TB without XDR among individuals who were HIV-negative in 2019. For HIV-positive individuals, the corresponding figures were approximately 47,000 (33,000-67,000) incident cases of MDR-TB and 19,000 (8,000-36,000) deaths due to MDR-TB in the same year. In 2019, higher numbers of incident cases and deaths were observed in males compared to females among individuals who were HIV-negative. Conversely, for HIV-positive individuals, females had higher numbers of incident cases and deaths compared to males. Specifically, the estimated numbers for incident cases were 23,000 (15,000-33,000) for females and 24,000 (17,000-35,000) for males, while the estimated numbers for deaths were 9,600 (4,000-17,900) for females and 9,800 (4,100-18,500) for males. Male-to-female ratios have remained above 1.0 from 1990 to 2019 in both incident cases and number of deaths for HIV-negative individuals. However, for HIV and MDR-TB coinfection, both ratios were below 1.0 in most of the time series. CONCLUSIONS: Males had more cases and deaths due to MDR-TB without XDR than females in HIV-negative patients, while females faced a higher incidence and mortality in HIV/AIDS-MDR-TB without XDR. Interventions are needed to deal with such factors, which increase the burden of coinfection among females across the world. © 2024 Verduci Editore s.r.l. All rights reserved. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Verduci | - |
dc.relation.isPartOf | EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Acquired Immunodeficiency Syndrome / drug therapy | - |
dc.subject.MESH | Acquired Immunodeficiency Syndrome / epidemiology | - |
dc.subject.MESH | Coinfection / epidemiology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Global Burden of Disease | - |
dc.subject.MESH | Global Health | - |
dc.subject.MESH | HIV Infections* / drug therapy | - |
dc.subject.MESH | HIV Infections* / epidemiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Sex Characteristics | - |
dc.subject.MESH | Sex Factors | - |
dc.subject.MESH | Tuberculosis, Multidrug-Resistant* / drug therapy | - |
dc.subject.MESH | Tuberculosis, Multidrug-Resistant* / epidemiology | - |
dc.title | Sex differences in the global burden of multidrug- resistant tuberculosis without extensive drug resistance in the general population and people living with HIV/AIDS, 1990-2019 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | J Choi | - |
dc.contributor.googleauthor | J Park | - |
dc.contributor.googleauthor | Y Son | - |
dc.contributor.googleauthor | S Kim | - |
dc.contributor.googleauthor | R Kwon | - |
dc.contributor.googleauthor | H Lee | - |
dc.contributor.googleauthor | M Rahmati | - |
dc.contributor.googleauthor | J Kang | - |
dc.contributor.googleauthor | H G Woo | - |
dc.contributor.googleauthor | A Koyanagi | - |
dc.contributor.googleauthor | L Smith | - |
dc.contributor.googleauthor | G F López Sánchez | - |
dc.contributor.googleauthor | E Dragioti | - |
dc.contributor.googleauthor | S-H Lee | - |
dc.contributor.googleauthor | W Cho | - |
dc.contributor.googleauthor | H J Kim | - |
dc.contributor.googleauthor | J I Shin | - |
dc.contributor.googleauthor | D K Yon | - |
dc.identifier.doi | 10.26355/eurrev_202405_36304 | - |
dc.contributor.localId | A02142 | - |
dc.relation.journalcode | J03872 | - |
dc.identifier.eissn | 2284-0729 | - |
dc.identifier.pmid | 38856143 | - |
dc.contributor.alternativeName | Shin, Jae Il | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.citation.volume | 28 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 3669 | - |
dc.citation.endPage | 3682 | - |
dc.identifier.bibliographicCitation | EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, Vol.28(10) : 3669-3682, 2024-05 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.