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Biomarkers for phenotype-endotype relationship in atopic dermatitis: a critical review

DC Field Value Language
dc.contributor.author박창욱-
dc.contributor.author이광훈-
dc.date.accessioned2024-06-14T02:51:58Z-
dc.date.available2024-06-14T02:51:58Z-
dc.date.issued2024-05-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/199743-
dc.description.abstractAtopic dermatitis (AD) is the most common form of chronic skin in fl ammation with diverse clinical variants. Historically, various AD phenotypes have been grouped together without considering their heterogeneity. This approach has resulted in a lack of phenotype- and endotype-adapted therapeutic strategies. Comprehensive insights into AD pathogenesis have enabled precise medicinal approach for AD. These efforts aimed to rede fi ne the endophenotype of AD and develop various biomarkers for diverse purposes. Among these endeavours, efforts are underway to elucidate the mechanisms (and related biomarkers) that lead to the emergence and progression of atopic diseases originating from AD (e.g., atopic march). This review focuses on diverse AD phenotypes and calls for a de fi nition of endophenotypes. While awaiting scienti fi c validation, these biomarkers ensure predicting disease onset and trajectory and tailoring therapeutic strategies for the future.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherElsevier-
dc.relation.isPartOfEBIOMEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAnimals-
dc.subject.MESHBiomarkers*-
dc.subject.MESHDermatitis, Atopic* / diagnosis-
dc.subject.MESHDermatitis, Atopic* / etiology-
dc.subject.MESHEndophenotypes Humans-
dc.subject.MESHPhenotype*-
dc.titleBiomarkers for phenotype-endotype relationship in atopic dermatitis: a critical review-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Dermatology (피부과학교실)-
dc.contributor.googleauthorChang Ook Park-
dc.contributor.googleauthorSu Min Kim-
dc.contributor.googleauthorKwang Hoon Lee-
dc.contributor.googleauthorThomas Bieber-
dc.identifier.doi10.1016/j.ebiom.2024.105121-
dc.contributor.localIdA01716-
dc.contributor.localIdA02674-
dc.relation.journalcodeJ03279-
dc.identifier.eissn2352-3964-
dc.identifier.pmid38614010-
dc.subject.keywordAtopic dermatitis-
dc.subject.keywordAtopic march-
dc.subject.keywordBiomarker-
dc.subject.keywordEndo-phenotype-
dc.subject.keywordPrecision medicine-
dc.contributor.alternativeNamePark, Chang Ook-
dc.contributor.affiliatedAuthor박창욱-
dc.contributor.affiliatedAuthor이광훈-
dc.citation.volume103-
dc.citation.startPage105121-
dc.identifier.bibliographicCitationEBIOMEDICINE, Vol.103 : 105121, 2024-05-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers

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