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Comparison of Survival Outcomes between Radical Antegrade Modular Pancreatosplenectomy and Conventional Distal Pancreatosplenectomy for Pancreatic Body and Tail Cancer: Korean Multicenter Propensity Score Match Analysis
DC Field | Value | Language |
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dc.contributor.author | 김성현 | - |
dc.date.accessioned | 2024-06-14T02:48:54Z | - |
dc.date.available | 2024-06-14T02:48:54Z | - |
dc.date.issued | 2024-04 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/199734 | - |
dc.description.abstract | (1) Background: The aim of this study was to compare the survival benefit of radical antegrade modular pancreatosplenectomy (RAMPS) with conventional distal pancreatosplenectomy (cDPS) in left-sided pancreatic cancer. (2) Methods: A retrospective propensity score matching (PSM) analysis was conducted on 333 patients who underwent RAMPS or cDPS for left-sided pancreatic cancer at four tertiary cancer centers. The study assessed prognostic factors and compared survival and operative outcomes. (3) Results: After PSM, 99 patients were matched in each group. RAMPS resulted in a higher retrieved lymph node count than cDPS (15.0 vs. 10.0, p < 0.001). No significant differences were observed between the two groups in terms of R0 resection rate, blood loss, hospital stay, or morbidity. The 5-year overall survival rate was similar in both groups (cDPS vs. RAMPS, 44.4% vs. 45.2%, p = 0.853), and disease-free survival was also comparable. Multivariate analysis revealed that ASA score, preoperative CA19-9, histologic differentiation, R1 resection, adjuvant treatment, and lymphovascular invasion were significant prognostic factors for overall survival. Preoperative CA19-9, histologic differentiation, T-stage, adjuvant treatment, and lymphovascular invasion were independent significant prognostic factors for disease-free survival. (4) Conclusions: Although RAMPS resulted in a higher retrieved lymph node count, survival outcomes were not different between the two groups. RAMPS was a surgical option to achieve R0 resection rather than a standard procedure. © 2024 by the authors. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | CANCERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Comparison of Survival Outcomes between Radical Antegrade Modular Pancreatosplenectomy and Conventional Distal Pancreatosplenectomy for Pancreatic Body and Tail Cancer: Korean Multicenter Propensity Score Match Analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Jaewoo Kwon | - |
dc.contributor.googleauthor | Huisong Lee | - |
dc.contributor.googleauthor | Hongbeom Kim | - |
dc.contributor.googleauthor | Sung Hyun Kim | - |
dc.contributor.googleauthor | Jae Do Yang | - |
dc.contributor.googleauthor | Woohyung Lee | - |
dc.contributor.googleauthor | Jun Suh Lee | - |
dc.contributor.googleauthor | Sang Hyun Shin | - |
dc.contributor.googleauthor | Hee Joon Kim | - |
dc.identifier.doi | 10.3390/cancers16081546 | - |
dc.contributor.localId | A04529 | - |
dc.relation.journalcode | J03449 | - |
dc.identifier.eissn | 2072-6694 | - |
dc.identifier.pmid | 38672628 | - |
dc.subject.keyword | pancreatectomy | - |
dc.subject.keyword | pancreatic neoplasm | - |
dc.subject.keyword | prognosis | - |
dc.subject.keyword | survival | - |
dc.contributor.alternativeName | Kim, Sung Hyun | - |
dc.contributor.affiliatedAuthor | 김성현 | - |
dc.citation.volume | 16 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1546 | - |
dc.identifier.bibliographicCitation | CANCERS, Vol.16(8) : 1546, 2024-04 | - |
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