Cited 0 times in
Clinical Trial to Reconfirm the Efficacy and Safety of Cefetamet Pivoxil Treatment in Sinusitis Patients: A Double-Blind, Randomized, Parallel Designed, Multicenter, Active Comparator Study (CASIS Study)
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김경수 | - |
dc.date.accessioned | 2024-05-31T06:17:51Z | - |
dc.date.available | 2024-05-31T06:17:51Z | - |
dc.date.issued | 2023-02 | - |
dc.identifier.issn | 0145-5613 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/199696 | - |
dc.description.abstract | Objective: To evaluate the clinical efficacy and safety of cefetamet pivoxil for the treatment of acute bacterial rhinosinusitis in Korean patients compared to treatment with cefdinir. Methods: A prospective, multicenter, randomized double-blind, comparative study was conducted by the Departments of Otorhinolaryngology-Head and Neck Surgery at 17 hospitals or universities in the Republic of Korea from March 2017 to April 2019. A total of 309 patients were screened and 249 patients participated in the study. Results: Treatment with cefetamet pivoxil for 2 weeks showed 82.4% clinical cure and improvement rates in patients with acute bacterial rhinosinusitis compared to 84.68% in those taking cefdinir for 2 weeks, showing that cefetamet pivoxil administered twice a day for 2 weeks was as effective as cefdinir 3 times a day for 2 weeks for the treatment of acute bacterial rhinosinusitis. The overall adverse reaction rates of both drugs were 10.56% in the cefetamet pivoxil group and 15.49% in the cefdinir group, without serious adverse events or drug reactions. Conclusions: Cefetamet pivoxil twice a day was as efficacious and safe as cefdinir 3 times a day for the treatment of acute bacterial rhinosinusitis, which suggested that cefetamet pivoxil may be a suitable alternative to cefdinir. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | SAGE Publications | - |
dc.relation.isPartOf | ENT-EAR NOSE & THROAT JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Bacteria | - |
dc.subject.MESH | Cefdinir | - |
dc.subject.MESH | Ceftizoxime* / adverse effects | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Sinusitis* / chemically induced | - |
dc.subject.MESH | Sinusitis* / drug therapy | - |
dc.title | Clinical Trial to Reconfirm the Efficacy and Safety of Cefetamet Pivoxil Treatment in Sinusitis Patients: A Double-Blind, Randomized, Parallel Designed, Multicenter, Active Comparator Study (CASIS Study) | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Otorhinolaryngology (이비인후과학교실) | - |
dc.contributor.googleauthor | Chan-Soon Park | - |
dc.contributor.googleauthor | Jin Hee Cho | - |
dc.contributor.googleauthor | Heung-Man Lee | - |
dc.contributor.googleauthor | Kyung-Su Kim | - |
dc.contributor.googleauthor | Jin Kook Kim | - |
dc.contributor.googleauthor | Dong-Young Kim | - |
dc.contributor.googleauthor | Byoung Joon Baek | - |
dc.contributor.googleauthor | Hyun Jun Kim | - |
dc.contributor.googleauthor | Yong-Dae Kim | - |
dc.contributor.googleauthor | Chi Sang Hwang | - |
dc.contributor.googleauthor | Seon Tae Kim | - |
dc.contributor.googleauthor | Seok Hyun Cho | - |
dc.contributor.googleauthor | Yong Min Kim | - |
dc.contributor.googleauthor | Seung Hoon Lee | - |
dc.contributor.googleauthor | Jin Hyeok Jeong | - |
dc.contributor.googleauthor | Seung Min In | - |
dc.contributor.googleauthor | Byung Guk Kim | - |
dc.identifier.doi | 10.1177/01455613211036236 | - |
dc.contributor.localId | A00298 | - |
dc.contributor.localId | A06616 | - |
dc.relation.journalcode | J04512 | - |
dc.identifier.eissn | 1942-7522 | - |
dc.identifier.pmid | 34427151 | - |
dc.identifier.url | https://journals.sagepub.com/doi/10.1177/01455613211036236 | - |
dc.subject.keyword | acute bacterial rhinosinusitis | - |
dc.subject.keyword | cefdinir | - |
dc.subject.keyword | cefetamet | - |
dc.subject.keyword | comparative study | - |
dc.subject.keyword | double-blinded method | - |
dc.contributor.alternativeName | Kim, Kyung Su | - |
dc.contributor.affiliatedAuthor | 김경수 | - |
dc.citation.volume | 102 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 101 | - |
dc.citation.endPage | 109 | - |
dc.identifier.bibliographicCitation | ENT-EAR NOSE & THROAT JOURNAL, Vol.102(2) : 101-109, 2023-02 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.