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Association between Sleep Duration and Incident Diabetes Mellitus in Healthy Subjects: A 14-Year Longitudinal Cohort Study
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dc.date.accessioned | 2024-05-30T07:09:35Z | - |
dc.date.available | 2024-05-30T07:09:35Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/199606 | - |
dc.description.abstract | Background: This study aimed to investigate whether sleep duration and/or quality are associated with incident diabetes mellitus (DM). Methods: A total of 8816 of 10,030 healthy participants were enrolled in a prospective cohort study. Sleep duration and quality questionnaires were completed. Sleep quality was assessed using the Epworth Sleepiness Scale (ESS), which measures excessive daytime sleepiness in individuals. Results: During the 14-year follow-up period, 18% (1630/8816) were diagnosed with DM. A U-shaped relationship was observed between sleep duration and incident DM, with the highest risk observed when sleep duration was >= 10 h/day (hazard ratios (HR) 1.65 [1.25-2.17]). This group exhibited decreased insulin glycogenic index, a marker of insulin secretory function, during the study period. Among study participants who slept less than 10 h/day, the risk of incident DM increased when the ESS score was >10. Conclusions: We found that the association between sleep duration and incident DM was U-shaped; both short (<= 5 h) and long (>= 10 h) sleep durations were associated with an increased risk for the occurrence of incident DM. When sleep duration was 10 h or longer per day, there was a tendency to develop DM due to decreased insulin secretory function. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI AG | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Association between Sleep Duration and Incident Diabetes Mellitus in Healthy Subjects: A 14-Year Longitudinal Cohort Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) | - |
dc.contributor.googleauthor | Jin Ha Jang | - |
dc.contributor.googleauthor | Wonjin Kim | - |
dc.contributor.googleauthor | Jin Sil Moon | - |
dc.contributor.googleauthor | Eun Roh | - |
dc.contributor.googleauthor | Jun Goo Kang | - |
dc.contributor.googleauthor | Seong Jin Lee | - |
dc.contributor.googleauthor | Sung-Hee Ihm | - |
dc.contributor.googleauthor | Ji Hye Huh | - |
dc.identifier.doi | 10.3390/jcm12082899 | - |
dc.relation.journalcode | J03556 | - |
dc.identifier.eissn | 2077-0383 | - |
dc.identifier.pmid | 37109236 | - |
dc.subject.keyword | diabetes | - |
dc.subject.keyword | excessive daytime sleepiness | - |
dc.subject.keyword | insulin secretion | - |
dc.subject.keyword | sleep duration | - |
dc.subject.keyword | sleep quality | - |
dc.citation.volume | 12 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 2899 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, Vol.12(8) : 2899, 2023-04 | - |
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