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Association between periodontal diseases and bipolar disorder: implications for therapeutic interventions
DC Field | Value | Language |
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dc.contributor.author | 정선재 | - |
dc.date.accessioned | 2024-05-30T06:52:29Z | - |
dc.date.available | 2024-05-30T06:52:29Z | - |
dc.date.issued | 2023-09 | - |
dc.identifier.issn | 2508-7940 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/199408 | - |
dc.description.abstract | Chronic low-grade inflammation plays a role in the pathophysiology of bipolar disorder. Recent studies have shown that periodontitis can affect the central nervous system by activating inflammatory mediators in the brain. However, only a few studies have ex-amined the association between periodontitis and bipolar disorder. Here, we aimed to review the current evidence on the association between periodontal diseases and bipo-lar disorder, its potential mechanisms, and future research directions. Studies so far suggested that periodontal diseases were more common in patients with bipolar disor-der than in the general population. Patients with bipolar disorder generally have poor oral hygiene owing to poor self-care, smoking, alcohol abuse, and the effects of psycho -tropic medications. Proposed mechanisms underlying this association include the ef-fects of inflammatory mediators, direct invasion of oral microbiota, modulation of the neurotransmitter system, and impact on the vagus nerve and hypothalamus -pitu-itary-adrenal axis. Additional clinical studies examining the prevalence of periodontal diseases and their association with the clinical features of bipolar disorder are neces-sary. Clinical studies targeting the treatment of periodontal diseases for primary or sec-ondary prevention of bipolar disorder are warranted. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Sungkyunkwan University School of Medicine | - |
dc.relation.isPartOf | PRECISION AND FUTURE MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Association between periodontal diseases and bipolar disorder: implications for therapeutic interventions | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine (예방의학교실) | - |
dc.contributor.googleauthor | Ji Hyun Baek | - |
dc.contributor.googleauthor | Sun Jae Jung | - |
dc.contributor.googleauthor | Amy Peters | - |
dc.contributor.googleauthor | Alpdogan Kantarci | - |
dc.contributor.googleauthor | Andrew A. Nierenberg | - |
dc.identifier.doi | 10.23838/pfm.2023.00086 | - |
dc.contributor.localId | A05546 | - |
dc.relation.journalcode | J04090 | - |
dc.identifier.eissn | 2508-7959 | - |
dc.contributor.alternativeName | Jung, Sun Jae | - |
dc.contributor.affiliatedAuthor | 정선재 | - |
dc.citation.volume | 7 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 117 | - |
dc.citation.endPage | 122 | - |
dc.identifier.bibliographicCitation | PRECISION AND FUTURE MEDICINE, Vol.7(3) : 117-122, 2023-09 | - |
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