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The higher recurrence rate after catheter ablation in younger patients with atrial fibrillation suggesting different pathophysiology
DC Field | Value | Language |
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dc.contributor.author | 박희남 | - |
dc.date.accessioned | 2024-05-30T06:48:23Z | - |
dc.date.available | 2024-05-30T06:48:23Z | - |
dc.date.issued | 2023-10 | - |
dc.identifier.issn | 1383-875X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/199348 | - |
dc.description.abstract | BackgroundYoung atrial fibrillation (AF) patients have been underrepresented in studies of radiofrequency catheter ablation (RFCA) and the outcome of RFCA has not been widely addressed. We investigated age-related differences in clinical features, the recurrence of atrial tachyarrhythmia, and its predictors of patients who underwent RFCA for AF.MethodsThis is a multicenter prospective study of 2799 patients who underwent RFCA for AF in 2017-2020. The patients were divided into two groups - group A (age < 60 years, n = 1269) and group B (age >= 60 years, n = 1530) - and a recurrence of any atrial tachyarrhythmia 1 year after RFCA following a 90-day blanking period was compared.ResultsThe mean age was 51.6 +/- 6.7 and 66.8 +/- 5.2 years for groups A and B, respectively. Higher body mass index, smaller left atrium, and more prevalent cardiomyopathy and obstructive sleep apnea were observed in group A. Overall, 1-year atrial tachyarrhythmia-free survival was 85.6% and lower in young patients (83.1% in group A vs. 87.7% in group B, log-rank p < 0.01): adjusted hazard ratio (aHR) of recurrence (95% confidence interval (CI)), 1.45 (1.13-1.86) for group A compared to group B (p < 0.01). The association between younger age and higher recurrence was continuously observed in patients under 60 years. Any non-PV ablation was associated with a lower recurrence of atrial tachyarrhythmia in group B (aHR 0.68 (0.47-0.96), p < 0.05), but not in group A.ConclusionsAF patients younger than 60 years had a higher 1-year AF recurrence after RFCA. Young AF patients might have distinctive pathophysiology of AF requiring more integrated management. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer | - |
dc.relation.isPartOf | JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Atrial Fibrillation* / surgery | - |
dc.subject.MESH | Catheter Ablation* | - |
dc.subject.MESH | Heart Atria / surgery | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Recurrence | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | The higher recurrence rate after catheter ablation in younger patients with atrial fibrillation suggesting different pathophysiology | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Hyo-Jeong Ahn | - |
dc.contributor.googleauthor | Myung-Jin Cha | - |
dc.contributor.googleauthor | Euijae Lee | - |
dc.contributor.googleauthor | So-Ryoung Lee | - |
dc.contributor.googleauthor | Eue-Keun Choi | - |
dc.contributor.googleauthor | Seongwook Han | - |
dc.contributor.googleauthor | Gi-Byung Nam | - |
dc.contributor.googleauthor | Jong-Il Choi | - |
dc.contributor.googleauthor | Hui-Nam Pak | - |
dc.contributor.googleauthor | Il-Young Oh | - |
dc.contributor.googleauthor | Dong-Gu Shin | - |
dc.contributor.googleauthor | Young Keun On | - |
dc.contributor.googleauthor | Sang Weon Park | - |
dc.contributor.googleauthor | Young-Hoon Kim | - |
dc.contributor.googleauthor | Seil Oh | - |
dc.contributor.googleauthor | KARA investigators | - |
dc.identifier.doi | 10.1007/s10840-022-01461-0 | - |
dc.contributor.localId | A01776 | - |
dc.relation.journalcode | J01464 | - |
dc.identifier.eissn | 1572-8595 | - |
dc.identifier.pmid | 36648614 | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s10840-022-01461-0 | - |
dc.subject.keyword | Age | - |
dc.subject.keyword | Atrial fibrillation | - |
dc.subject.keyword | Radiofrequency catheter ablation | - |
dc.subject.keyword | Recurrence | - |
dc.subject.keyword | Young | - |
dc.contributor.alternativeName | Pak, Hui Nam | - |
dc.contributor.affiliatedAuthor | 박희남 | - |
dc.citation.volume | 66 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1609 | - |
dc.citation.endPage | 1619 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY, Vol.66(7) : 1609-1619, 2023-10 | - |
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