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Use of Baclofen as a Treatment for Nocturnal Calf Cramps in Individuals With Lumbar Spinal Stenosis: A Prospective Randomized Study
DC Field | Value | Language |
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dc.contributor.author | 김신형 | - |
dc.contributor.author | 김희정 | - |
dc.contributor.author | 윤경봉 | - |
dc.contributor.author | 강미선 | - |
dc.date.accessioned | 2024-05-23T03:27:39Z | - |
dc.date.available | 2024-05-23T03:27:39Z | - |
dc.date.issued | 2024-05 | - |
dc.identifier.issn | 0894-9115 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/199232 | - |
dc.description.abstract | Objective: This study aimed to compare the efficacy and safety of baclofen and gabapentin in reducing leg pain from nocturnal calf cramps in lumbar spinal stenosis patients. Design: In a randomized clinical trial, the patients with lumbar spinal stenosis who commonly experienced nocturnal calf cramps were included. Patients were randomly assigned to either the baclofen or gabapentin group. Overall leg pain intensity, nocturnal calf cramp frequency and severity, sleep disturbances and functional disability were assessed at baseline and after 4 and 12 wks. Results: Thirty-six patients completed the 3-mo study. Both gabapentin and baclofen groups showed a significant reduction in overall leg pain, calf cramp frequency and intensity, and insomnia severity index scores from baseline to the endpoint. However, there were no significant differences between the two groups in terms of symptom reduction at different time points. The baclofen group also demonstrated a significant decrease in Oswestry Disability Index scores ( P < 0.001), while the gabapentin group did not ( P = 0.344). No adverse effects were reported in either group. Conclusions: Baclofen seems to be as effective and as safe as gabapentin in treating nocturnal calf cramps in lumbar spinal stenosis patients and even shows superiority in enhancing functional outcomes. Trial registration: ClinicalTrials.gov NCT05392361. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Baclofen / therapeutic use | - |
dc.subject.MESH | Gabapentin / therapeutic use | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Leg | - |
dc.subject.MESH | Lumbar Vertebrae | - |
dc.subject.MESH | Muscle Cramp | - |
dc.subject.MESH | Pain | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Spinal Stenosis* / complications | - |
dc.subject.MESH | Spinal Stenosis* / drug therapy | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Use of Baclofen as a Treatment for Nocturnal Calf Cramps in Individuals With Lumbar Spinal Stenosis: A Prospective Randomized Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Hee Jung Kim | - |
dc.contributor.googleauthor | Kyung Bong Yoon | - |
dc.contributor.googleauthor | Misun Kang | - |
dc.contributor.googleauthor | Hee Won Lee | - |
dc.contributor.googleauthor | Shin Hyung Kim | - |
dc.identifier.doi | 10.1097/phm.0000000000002364 | - |
dc.contributor.localId | A00676 | - |
dc.contributor.localId | A06251 | - |
dc.relation.journalcode | J00101 | - |
dc.identifier.eissn | 1537-7385 | - |
dc.identifier.pmid | 38063320 | - |
dc.identifier.url | https://journals.lww.com/ajpmr/fulltext/2024/05000/use_of_baclofen_as_a_treatment_for_nocturnal_calf.3.aspx | - |
dc.contributor.alternativeName | Kim, Shin Hyung | - |
dc.contributor.affiliatedAuthor | 김신형 | - |
dc.contributor.affiliatedAuthor | 김희정 | - |
dc.citation.volume | 103 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 384 | - |
dc.citation.endPage | 389 | - |
dc.identifier.bibliographicCitation | AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, Vol.103(5) : 384-389, 2024-05 | - |
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