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Evaluation of the deliverability of dynamic conformal arc therapy (DCAT) by gantry wobble and its influence on dose

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dc.contributor.author김동욱-
dc.contributor.author김진성-
dc.contributor.author김창환-
dc.contributor.author김호진-
dc.contributor.author성진실-
dc.contributor.author이호-
dc.contributor.author한민철-
dc.contributor.author홍채선-
dc.date.accessioned2024-05-23T02:55:17Z-
dc.date.available2024-05-23T02:55:17Z-
dc.date.issued2024-03-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/199109-
dc.description.abstractWe aimed to investigate the deliverability of dynamic conformal arc therapy (DCAT) by gantry wobble owing to the intrinsic inter-segment break of the Elekta linear accelerator (LINAC) and its adverse influence on the dose to the patient. The deliverability of DCAT was evaluated according to the plan parameters, which affect the gantry rotation speed and resultant positional inaccuracies; the deliverability according to the number of control points and dose rates was investigated by using treatment machine log files and dosimetry devices, respectively. A non-negligible degradation in DCAT deliverability due to gantry wobble was observed in both the treatment machine log files and dosimetry devices. The resulting dose-delivery error occurred below a certain number of control points or above a certain dose rate. Dose simulations in the patient domain showed a similar impact on deteriorated deliverability. For targets located primarily in the isocenter, the dose differences were negligible, whereas for organs at risk located mainly off-isocenter, the dose differences were significant up to − 8.77%. To ensure safe and accurate radiotherapy, optimal plan parameters should be selected, and gantry angle-specific validations should be conducted before treatment. © The Author(s) 2024.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherNature Publishing Group-
dc.relation.isPartOfSCIENTIFIC REPORTS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHHumans-
dc.subject.MESHParticle Accelerators-
dc.subject.MESHRadiometry / methods-
dc.subject.MESHRadiotherapy Dosage-
dc.subject.MESHRadiotherapy Planning, Computer-Assisted / methods-
dc.subject.MESHRadiotherapy, Conformal* / methods-
dc.subject.MESHRadiotherapy, Intensity-Modulated* / methods-
dc.titleEvaluation of the deliverability of dynamic conformal arc therapy (DCAT) by gantry wobble and its influence on dose-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiation Oncology (방사선종양학교실)-
dc.contributor.googleauthorChanghwan Kim-
dc.contributor.googleauthorHojae Kim-
dc.contributor.googleauthorDongmin Jung-
dc.contributor.googleauthorHeesoo Kim-
dc.contributor.googleauthorYeonok Park-
dc.contributor.googleauthorMin Cheol Han-
dc.contributor.googleauthorChae-Seon Hong-
dc.contributor.googleauthorHojin Kim-
dc.contributor.googleauthorHo Lee-
dc.contributor.googleauthorJinsil Sung-
dc.contributor.googleauthorDong Wook Kim-
dc.contributor.googleauthorJin Sung Kim-
dc.identifier.doi10.1038/s41598-024-57644-4-
dc.contributor.localIdA05710-
dc.contributor.localIdA04548-
dc.contributor.localIdA06353-
dc.contributor.localIdA05970-
dc.contributor.localIdA01956-
dc.contributor.localIdA03323-
dc.contributor.localIdA05870-
dc.contributor.localIdA05846-
dc.relation.journalcodeJ02646-
dc.identifier.eissn2045-2322-
dc.identifier.pmid38532018-
dc.contributor.alternativeNameKim, Dong Wook-
dc.contributor.affiliatedAuthor김동욱-
dc.contributor.affiliatedAuthor김진성-
dc.contributor.affiliatedAuthor김창환-
dc.contributor.affiliatedAuthor김호진-
dc.contributor.affiliatedAuthor성진실-
dc.contributor.affiliatedAuthor이호-
dc.contributor.affiliatedAuthor한민철-
dc.contributor.affiliatedAuthor홍채선-
dc.citation.volume14-
dc.citation.number1-
dc.citation.startPage7134-
dc.identifier.bibliographicCitationSCIENTIFIC REPORTS, Vol.14(1) : 7134, 2024-03-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers

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