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Azoospermic Men with a History of Cryptorchidism Treated by Orchiopexy Have Favorable Outcomes after Testicular Sperm Extraction: A Systematic Review and Meta-Analysis

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dc.contributor.author김상운-
dc.contributor.author이종수-
dc.date.accessioned2024-03-27T00:55:03Z-
dc.date.available2024-03-27T00:55:03Z-
dc.date.issued2023-01-
dc.identifier.issn2287-4208-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/198780-
dc.description.abstractPurpose: This systematic review and meta-analysis investigated the sperm retrieval rate (SRR) and pregnancy rate after testicular sperm extraction in men with azoospermia and those with a history of cryptorchidism treated by orchiopexy. Materials and methods: The SRR and clinical pregnancy rate were investigated. We performed a sub-analysis that included factors such as bilaterality, age, and idiopathic non-obstructive azoospermia (iNOA). The analysis comprised 13 studies from January 1995 to July 2021. The data sources were PubMed/MEDLINE, Embase, and the Cochrane Library included "cryptorchidism", "orchidopexy", "azoospermia", and "testicular sperm extraction". Results: The overall mean SRR was 63.3% (95% confidence interval [CI], 57.6%-68.6%; I²=62.4%), and the overall mean clinical pregnancy rate was 30.1% (95% CI, 22.6%-38.8%; I²=69.9%). The meta-analysis comparing the SRR, there was no significant difference between patients with a history of bilateral and unilateral orchiopexy (relative risk [RR]=1.02; 95% CI, 0.89-1.16; p=0.79). Orchiopexy performed under the age of 10 years showed significantly increased SRR compared to the age of over 10 years (RR=1.25; 95% CI, 1.06-1.47; p=0.008). Azoospermic men with a history of cryptorchidism treated by orchiopexy had significantly higher SRR than iNOA (RR=1.90; 95% CI, 1.40-2.58; p<0.0001). Conclusions: Men with azoospermia and a history of cryptorchidism treated by orchiopexy had significantly higher SRR than those with iNOA after testicular sperm extraction. Furthermore, patients who underwent orchiopexy before the age of ten years had significantly higher SRR than patients operated at an older than the age of ten years.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisher대한남성과학회-
dc.relation.isPartOfWORLD JOURNAL OF MENS HEALTH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleAzoospermic Men with a History of Cryptorchidism Treated by Orchiopexy Have Favorable Outcomes after Testicular Sperm Extraction: A Systematic Review and Meta-Analysis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthorSang Woon Kim-
dc.contributor.googleauthorJongsoo Lee-
dc.contributor.googleauthorTae Ho Lee-
dc.contributor.googleauthorDong Suk Kim-
dc.contributor.googleauthorSeung-Hun Song-
dc.contributor.googleauthorDae Keun Kim-
dc.identifier.doi10.5534/wjmh.210198-
dc.contributor.localIdA00527-
dc.contributor.localIdA05500-
dc.relation.journalcodeJ02798-
dc.identifier.eissn2287-4690-
dc.identifier.pmid35274507-
dc.subject.keywordAzoospermia-
dc.subject.keywordCryptorchidism-
dc.subject.keywordMeta-analysis-
dc.subject.keywordTesticular sperm retrieval-
dc.contributor.alternativeNameKim, Sang Woon-
dc.contributor.affiliatedAuthor김상운-
dc.contributor.affiliatedAuthor이종수-
dc.citation.volume41-
dc.citation.number1-
dc.citation.startPage81-
dc.citation.endPage93-
dc.identifier.bibliographicCitationWORLD JOURNAL OF MENS HEALTH, Vol.41(1) : 81-93, 2023-01-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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