Cited 0 times in
CSMP: A Self-Assembled Plant Polysaccharide-Based Hydrofilm for Enhanced Wound Healing
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박창욱 | - |
dc.date.accessioned | 2024-03-22T07:18:27Z | - |
dc.date.available | 2024-03-22T07:18:27Z | - |
dc.date.issued | 2024-03 | - |
dc.identifier.issn | 2192-2640 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/198733 | - |
dc.description.abstract | Wound management remains a critical healthcare issue due to the rising incidence of chronic diseases leading to persistent wounds. Traditional dressings have their limitations, such as potential for further damage during changing and suboptimal healing conditions. Recently, hydrogel-based dressings have gained attention due to their biocompatibility, biodegradability, and ability to fill wounds. Particularly, polysaccharide-based hydrogels have shown potential in various medical applications. This study focuses on the development of a novel hydrofilm wound dressing produced from a blend of chia seed mucilage (CSM) and polyvinyl alcohol (PVA), termed CSMP. While the individual properties of CSM and PVA are well-documented, their combined potential in wound management is largely unexplored. CSMP, coupled with sorbitol and glycerin, and cross-linked using ultraviolet light, results in a flexible, adhesive, and biocompatible hydrofilm demonstrating superior water absorption, moisturizing, and antibacterial properties. This hydrofilm promotes epithelial cell migration, enhanced collagen production, and outperforms existing commercial dressings in animal tests. The innovative CSMP hydrofilm offers a promising, cost-effective approach for improved wound care, bridging existing gaps in dressing performance and preparation simplicity. Future research can unlock further applications of such polysaccharide-based hydrofilm dressings. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isPartOf | ADVANCED HEALTHCARE MATERIALS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Anti-Bacterial Agents* | - |
dc.subject.MESH | Bandages | - |
dc.subject.MESH | Cell Movement | - |
dc.subject.MESH | Glycerol / pharmacology | - |
dc.subject.MESH | Hydrogels / pharmacology | - |
dc.subject.MESH | Wound Healing* | - |
dc.title | CSMP: A Self-Assembled Plant Polysaccharide-Based Hydrofilm for Enhanced Wound Healing | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Dermatology (피부과학교실) | - |
dc.contributor.googleauthor | Zhen Qiao | - |
dc.contributor.googleauthor | KeLun Zhang | - |
dc.contributor.googleauthor | Huifang Liu | - |
dc.contributor.googleauthor | Yeonjeong Roh | - |
dc.contributor.googleauthor | Myoung Gyu Kim | - |
dc.contributor.googleauthor | Hyo Joo Lee | - |
dc.contributor.googleauthor | Bonhan Koo | - |
dc.contributor.googleauthor | Eun Yeong Lee | - |
dc.contributor.googleauthor | Minju Lee | - |
dc.contributor.googleauthor | Chang Ook Park | - |
dc.contributor.googleauthor | Yong Shin | - |
dc.identifier.doi | 10.1002/adhm.202303244 | - |
dc.contributor.localId | A01716 | - |
dc.relation.journalcode | J00042 | - |
dc.identifier.eissn | 2192-2659 | - |
dc.identifier.pmid | 37934913 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1002/adhm.202303244 | - |
dc.subject.keyword | antibacterial effects | - |
dc.subject.keyword | chia mucilage | - |
dc.subject.keyword | hydrofilms | - |
dc.subject.keyword | tissue adhesiveness | - |
dc.subject.keyword | wound healing | - |
dc.contributor.alternativeName | Park, Chang Ook | - |
dc.contributor.affiliatedAuthor | 박창욱 | - |
dc.citation.volume | 13 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1 | - |
dc.citation.endPage | 15 | - |
dc.identifier.bibliographicCitation | ADVANCED HEALTHCARE MATERIALS, Vol.13(6) : 1-15, 2024-03 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.