Cited 2 times in
Persistent and Recurrent Device-Related Thrombus After Left Atrial Appendage Closure: Incidence, Predictors, and Outcomes
DC Field | Value | Language |
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dc.contributor.author | 이오현 | - |
dc.contributor.author | 김중선 | - |
dc.date.accessioned | 2024-03-22T06:07:33Z | - |
dc.date.available | 2024-03-22T06:07:33Z | - |
dc.date.issued | 2023-11 | - |
dc.identifier.issn | 1936-8798 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/198407 | - |
dc.description.abstract | Background: Scarce data exist on the evolution of device-related thrombus (DRT) after left atrial appendage closure (LAAC). Objectives: This study sought to assess the incidence, predictors, and clinical impact of persistent and recurrent DRT in LAAC recipients. Methods: Data were obtained from an international multicenter registry including 237 patients diagnosed with DRT after LAAC. Of these, 214 patients with a subsequent imaging examination after the initial diagnosis of DRT were included. Unfavorable evolution of DRT was defined as either persisting or recurrent DRT. Results: DRT resolved in 153 (71.5%) cases and persisted in 61 (28.5%) cases. Larger DRT size (OR per 1-mm increase: 1.08; 95% CI: 1.02-1.15; P = 0.009) and female (OR: 2.44; 95% CI: 1.12-5.26; P = 0.02) were independently associated with persistent DRT. After DRT resolution, 82 (53.6%) of 153 patients had repeated device imaging, with 14 (17.1%) cases diagnosed with recurrent DRT. Overall, 75 (35.0%) patients had unfavorable evolution of DRT, and the sole predictor was average thrombus size at initial diagnosis (OR per 1-mm increase: 1.09; 95% CI: 1.03-1.16; P = 0.003), with an optimal cutoff size of 7 mm (OR: 2.51; 95% CI: 1.39-4.52; P = 0.002). Unfavorable evolution of DRT was associated with a higher rate of thromboembolic events compared with resolved DRT (26.7% vs 15.1%; HR: 2.13; 95% CI: 1.15-3.94; P = 0.02). Conclusions: About one-third of DRT events had an unfavorable evolution (either persisting or recurring), with a larger initial thrombus size (particularly >7 mm) portending an increased risk. Unfavorable evolution of DRT was associated with a 2-fold higher risk of thromboembolic events compared with resolved DRT. © 2023 American College of Cardiology Foundation | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JACC-CARDIOVASCULAR INTERVENTIONS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Atrial Appendage* / diagnostic imaging | - |
dc.subject.MESH | Atrial Fibrillation* / complications | - |
dc.subject.MESH | Atrial Fibrillation* / epidemiology | - |
dc.subject.MESH | Atrial Fibrillation* / therapy | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Incidence | - |
dc.subject.MESH | Stroke* / etiology | - |
dc.subject.MESH | Thromboembolism* / diagnostic imaging | - |
dc.subject.MESH | Thromboembolism* / epidemiology | - |
dc.subject.MESH | Thromboembolism* / etiology | - |
dc.subject.MESH | Thrombosis* / diagnostic imaging | - |
dc.subject.MESH | Thrombosis* / epidemiology | - |
dc.subject.MESH | Thrombosis* / etiology | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Persistent and Recurrent Device-Related Thrombus After Left Atrial Appendage Closure: Incidence, Predictors, and Outcomes | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jules Mesnier | - |
dc.contributor.googleauthor | Trevor Simard | - |
dc.contributor.googleauthor | Richard G Jung | - |
dc.contributor.googleauthor | Kyle R Lehenbauer | - |
dc.contributor.googleauthor | Kerstin Piayda | - |
dc.contributor.googleauthor | Radoslaw Pracon | - |
dc.contributor.googleauthor | Gregory G Jackson | - |
dc.contributor.googleauthor | Eduardo Flores-Umanzor | - |
dc.contributor.googleauthor | Laurent Faroux | - |
dc.contributor.googleauthor | Kasper Korsholm | - |
dc.contributor.googleauthor | Julian K R Chun | - |
dc.contributor.googleauthor | Shaojie Chen | - |
dc.contributor.googleauthor | Moniek Maarse | - |
dc.contributor.googleauthor | Kristi Montrella | - |
dc.contributor.googleauthor | Zakeih Chaker | - |
dc.contributor.googleauthor | Jocelyn N Spoon | - |
dc.contributor.googleauthor | Luigi E Pastormerlo | - |
dc.contributor.googleauthor | Felix Meincke | - |
dc.contributor.googleauthor | Abhishek C Sawant | - |
dc.contributor.googleauthor | Carmen M Moldovan | - |
dc.contributor.googleauthor | Mohammed Qintar | - |
dc.contributor.googleauthor | Mehmet K Aktas | - |
dc.contributor.googleauthor | Luca Branca | - |
dc.contributor.googleauthor | Andrea Radinovic | - |
dc.contributor.googleauthor | Pradhum Ram | - |
dc.contributor.googleauthor | Rayan S El-Zein | - |
dc.contributor.googleauthor | Thomas Flautt | - |
dc.contributor.googleauthor | Wern Yew Ding | - |
dc.contributor.googleauthor | Bassel Sayegh | - |
dc.contributor.googleauthor | Tomás Benito-González | - |
dc.contributor.googleauthor | Oh-Hyun Lee | - |
dc.contributor.googleauthor | Solomon O Badejoko | - |
dc.contributor.googleauthor | Christina Paitazoglou | - |
dc.contributor.googleauthor | Nabeela Karim | - |
dc.contributor.googleauthor | Ahmed M Zaghloul | - |
dc.contributor.googleauthor | Himanshu Agarwal | - |
dc.contributor.googleauthor | Rachel M Kaplan | - |
dc.contributor.googleauthor | Oluseun Alli | - |
dc.contributor.googleauthor | Aamir Ahmed | - |
dc.contributor.googleauthor | Hussam S Suradi | - |
dc.contributor.googleauthor | Bradley P Knight | - |
dc.contributor.googleauthor | Venkata M Alla | - |
dc.contributor.googleauthor | Sidakpal S Panaich | - |
dc.contributor.googleauthor | Tom Wong | - |
dc.contributor.googleauthor | Martin W Bergmann | - |
dc.contributor.googleauthor | Rashaad Chothia | - |
dc.contributor.googleauthor | Jung-Sun Kim | - |
dc.contributor.googleauthor | Armando Pérez de Prado | - |
dc.contributor.googleauthor | Raveen Bazaz | - |
dc.contributor.googleauthor | Dhiraj Gupta | - |
dc.contributor.googleauthor | Miguel Valderrábano | - |
dc.contributor.googleauthor | Carlos E Sanchez | - |
dc.contributor.googleauthor | Mikhael F El Chami | - |
dc.contributor.googleauthor | Patrizio Mazzone | - |
dc.contributor.googleauthor | Marianna Adamo | - |
dc.contributor.googleauthor | Fred Ling | - |
dc.contributor.googleauthor | Dee Dee Wang | - |
dc.contributor.googleauthor | William O'Neill | - |
dc.contributor.googleauthor | Wojtek Wojakowski | - |
dc.contributor.googleauthor | Ashish Pershad | - |
dc.contributor.googleauthor | Sergio Berti | - |
dc.contributor.googleauthor | Daniel B Spoon | - |
dc.contributor.googleauthor | Akram Kawsara | - |
dc.contributor.googleauthor | George Jabbour | - |
dc.contributor.googleauthor | Lucas V A Boersma | - |
dc.contributor.googleauthor | Boris Schmidt | - |
dc.contributor.googleauthor | Jens Erik Nielsen-Kudsk | - |
dc.contributor.googleauthor | Xavier Freixa | - |
dc.contributor.googleauthor | Christopher R Ellis | - |
dc.contributor.googleauthor | Laurent Fauchier | - |
dc.contributor.googleauthor | Marcin Demkow | - |
dc.contributor.googleauthor | Horst Sievert | - |
dc.contributor.googleauthor | Michael L Main | - |
dc.contributor.googleauthor | Benjamin Hibbert | - |
dc.contributor.googleauthor | David R Holmes Jr | - |
dc.contributor.googleauthor | Mohamad Alkhouli | - |
dc.contributor.googleauthor | Josep Rodés-Cabau | - |
dc.identifier.doi | 10.1016/j.jcin.2023.09.017 | - |
dc.contributor.localId | A05164 | - |
dc.relation.journalcode | J01193 | - |
dc.identifier.eissn | 1876-7605 | - |
dc.identifier.pmid | 38030358 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1936879823013110 | - |
dc.subject.keyword | atrial fibrillation | - |
dc.subject.keyword | device-related thrombus | - |
dc.subject.keyword | left atrial appendage occlusion | - |
dc.subject.keyword | stroke | - |
dc.contributor.alternativeName | Lee, Oh Hyun | - |
dc.contributor.affiliatedAuthor | 이오현 | - |
dc.citation.volume | 16 | - |
dc.citation.number | 22 | - |
dc.citation.startPage | 2722 | - |
dc.citation.endPage | 2732 | - |
dc.identifier.bibliographicCitation | JACC-CARDIOVASCULAR INTERVENTIONS, Vol.16(22) : 2722-2732, 2023-11 | - |
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