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Noninvasive hemoglobin monitoring for maintaining hemoglobin concentration within the target range during major noncardiac surgery: A randomized controlled trial
DC Field | Value | Language |
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dc.contributor.author | 박선경 | - |
dc.contributor.author | 김영원 | - |
dc.date.accessioned | 2024-03-22T05:36:58Z | - |
dc.date.available | 2024-03-22T05:36:58Z | - |
dc.date.issued | 2024-05 | - |
dc.identifier.issn | 0952-8180 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/198128 | - |
dc.description.abstract | Study objective: The effect of noninvasive CO-oximetry hemoglobin (SpHb) monitoring on the clinical outcomes of patients undergoing surgery remains unclear. This trial aimed to evaluate whether SpHb monitoring helps maintain hemoglobin levels within a predefined target range during major noncardiac surgeries with a potential risk of intraoperative hemorrhage. Design: A single-center, prospective, randomized controlled trial. Setting: University hospital. Patients: One hundred and thirty patients undergoing elective noncardiac surgery with a potential risk of hemorrhage. Interventions: Patients were randomly allocated to undergo either SpHb-guided management (SpHb group) or usual care (control group). Measurements: The primary outcome was the rate of deviation of the total hemoglobin concentration (determined from laboratory testing) from a pre-specified target range (8–14 g/dL). This was defined as the number of laboratory tests revealing such deviations divided by the total number of laboratory tests performed during the surgery. Main results: The primary outcome occurred significantly less frequently in the SpHb group as compared to that in the control group (15/555 [2.7%]) vs. 68/598 [11.4%]; relative risk, 0.24; 95% confidence interval, 0.13–0.41; P < 0.001). Fewer point-of-care blood tests were performed in the SpHb group than in the control group (median [interquartile range], 2 [1–4] vs. 4 [2–5]; P < 0.001). There were no significant intergroup differences in the number of patients who received red blood cell transfusions during surgery (SpHb vs. control, 33.8% vs. 46.2%; P = 0.201). The incidence of unnecessary red blood cell preparation (>2 units) was lower in the SpHb group than in the control group (3.1% vs. 16.9%; P = 0.024). Conclusions: Compared with routine care, SpHb-guided management resulted in significantly lower rates of hemoglobin deviation outside the target range intraoperatively in patients undergoing major noncardiac surgeries with a potential risk of hemorrhage. Clinical trial registration: ClinicalTrials.gov (identifier: NCT03816514). © 2023 Elsevier Inc. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL ANESTHESIA | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Blood Loss, Surgical / prevention & control | - |
dc.subject.MESH | Hemoglobins / analysis | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Monitoring, Intraoperative* / methods | - |
dc.subject.MESH | Oximetry* / methods | - |
dc.subject.MESH | Prospective Studies | - |
dc.title | Noninvasive hemoglobin monitoring for maintaining hemoglobin concentration within the target range during major noncardiac surgery: A randomized controlled trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Sun-Kyung Park | - |
dc.contributor.googleauthor | Chahnmee Hur | - |
dc.contributor.googleauthor | Young-Won Kim | - |
dc.contributor.googleauthor | Seokha Yoo | - |
dc.contributor.googleauthor | Young-Jin Lim | - |
dc.contributor.googleauthor | Jin-Tae Kim | - |
dc.identifier.doi | 10.1016/j.jclinane.2023.111326 | - |
dc.contributor.localId | A06339 | - |
dc.relation.journalcode | J01315 | - |
dc.identifier.eissn | 1873-4529 | - |
dc.identifier.pmid | 37988814 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0952818023002763 | - |
dc.subject.keyword | Blood loss | - |
dc.subject.keyword | Blood transfusion | - |
dc.subject.keyword | Hemoglobins | - |
dc.subject.keyword | Noncardiac surgery | - |
dc.subject.keyword | Noninvasive hemoglobin monitoring | - |
dc.subject.keyword | Surgical | - |
dc.contributor.alternativeName | Park, Sun-Kyung | - |
dc.contributor.affiliatedAuthor | 박선경 | - |
dc.citation.volume | 93 | - |
dc.citation.startPage | 111326 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL ANESTHESIA, Vol.93 : 111326, 2024-05 | - |
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