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Prediction of Stent Failure for Malignant Ureteral Obstruction in Non-Urological Cancer
DC Field | Value | Language |
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dc.contributor.author | 이종수 | - |
dc.contributor.author | 장원식 | - |
dc.contributor.author | 한현호 | - |
dc.contributor.author | 허지은 | - |
dc.contributor.author | 전대영 | - |
dc.date.accessioned | 2024-02-15T06:29:36Z | - |
dc.date.available | 2024-02-15T06:29:36Z | - |
dc.date.issued | 2023-11 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/197930 | - |
dc.description.abstract | Purpose: To analyze prognostic factors associated with ureteral stent failure and to develop a prediction model for malignant ure teral obstruction (MUO) in patients with non-urological cancers. Materials and Methods: We retrospectively reviewed patients with non-urological cancers who underwent ureteral stenting or percutaneous nephrostomy (PCN) for MUO between 2006 and 2014. Variables predicting stent failure were identified using Cox regression analysis. Results: Of the 743 patients, 468 (63.0%) underwent ureteral stenting only, and 275 (37.0%) underwent PCN owing to technical (n=215) or functional (n=60) stent failure. The median overall survival was 4 [interquartile range (IQR) 1–11] months, and the me dian interval duration to stent failure was 2 (IQR 0–7) months. In univariate analysis, lower gastrointestinal cancer, previous radio therapy to the pelvis, bladder invasion, lower ureteral obstruction, and low previous estimated glomerular filtration rate (eGFR) (<30 mL/min/1.73 m2) were significantly associated with a decreased survival rate. In multivariate analysis, bladder invasion and previous eGFR were significant predictors. With these two predictors, we divided patients into three groups based on their pres ence: low-risk (neither factor; n=516), intermediate-risk (one factor; n=206), and high-risk (both factors; n=21). The median stent failure-free survival rates of patients in the low-, intermediate-, and high-risk groups were 26 (8-unreached), 1 (0–18), and 0 (0–0) months, respectively (p<0.001). Conclusion: In cases of ureteral obstruction caused by non-urological cancers, patients with bladder invasion and a low eGFR showed poor stent failure-free survival. Therefore, PCN should be considered the primary procedure for these patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Neoplasms* | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Stents / adverse effects | - |
dc.subject.MESH | Ureteral Obstruction* / complications | - |
dc.subject.MESH | Ureteral Obstruction* / surgery | - |
dc.title | Prediction of Stent Failure for Malignant Ureteral Obstruction in Non-Urological Cancer | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Ji Eun Heo | - |
dc.contributor.googleauthor | Dae Young Jeon | - |
dc.contributor.googleauthor | Jongsoo Lee | - |
dc.contributor.googleauthor | Hyun Ho Han | - |
dc.contributor.googleauthor | Won Sik Jang | - |
dc.identifier.doi | 10.3349/ymj.2023.0117 | - |
dc.contributor.localId | A05500 | - |
dc.contributor.localId | A05268 | - |
dc.contributor.localId | A04333 | - |
dc.contributor.localId | A05531 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 37880847 | - |
dc.subject.keyword | Percutaneous nephrostomy | - |
dc.subject.keyword | survival | - |
dc.subject.keyword | ureteral obstruction | - |
dc.subject.keyword | urinary diversion | - |
dc.contributor.alternativeName | Lee, Jong Soo | - |
dc.contributor.affiliatedAuthor | 이종수 | - |
dc.contributor.affiliatedAuthor | 장원식 | - |
dc.contributor.affiliatedAuthor | 한현호 | - |
dc.contributor.affiliatedAuthor | 허지은 | - |
dc.citation.volume | 64 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 665 | - |
dc.citation.endPage | 669 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.64(11) : 665-669, 2023-11 | - |
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