Cited 2 times in
Recent advances in cellular immunotherapy for lymphoid malignancies
DC Field | Value | Language |
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dc.contributor.author | 정해림 | - |
dc.contributor.author | 조현수 | - |
dc.date.accessioned | 2024-01-16T02:02:17Z | - |
dc.date.available | 2024-01-16T02:02:17Z | - |
dc.date.issued | 2023-12 | - |
dc.identifier.issn | 2287-979X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/197834 | - |
dc.description.abstract | Cellular immunotherapy with chimeric antigen receptor (CAR) T-cells has revolutionized the treatment of lymphoid malignancies. This review addresses the need for CAR expression in our endogenous T-cells to kill tumor cells with a focus on the basic principles of T-cell receptor recognition of major histocompatibility complex-peptide complexes. We review the factors associated with CAR T-cell outcomes and recent efforts to employ CAR T-cells in earlier lines of therapy. We also discuss the value of bispecific T-cell engagers as off-the-shelf products with better toxicity profiles. Finally, natural killer cells are discussed as an important cellular immunotherapy platform with the potential to broaden immunotherapeutic applications beyond lymphoid malignancies. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korea Society of Hematology | - |
dc.relation.isPartOf | BLOOD RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Recent advances in cellular immunotherapy for lymphoid malignancies | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Haerim Chung | - |
dc.contributor.googleauthor | Hyunsoo Cho | - |
dc.identifier.doi | 10.5045/br.2023.2023177 | - |
dc.contributor.localId | A04674 | - |
dc.contributor.localId | A03929 | - |
dc.relation.journalcode | J00346 | - |
dc.identifier.eissn | 2288-0011 | - |
dc.identifier.pmid | 37964655 | - |
dc.subject.keyword | Cellular immunotherapy | - |
dc.subject.keyword | Chimeric antigen receptor T cells | - |
dc.subject.keyword | Lymphoma | - |
dc.subject.keyword | Multiple myeloma | - |
dc.contributor.alternativeName | Chung, Hae Rim | - |
dc.contributor.affiliatedAuthor | 정해림 | - |
dc.contributor.affiliatedAuthor | 조현수 | - |
dc.citation.volume | 58 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 166 | - |
dc.citation.endPage | 172 | - |
dc.identifier.bibliographicCitation | BLOOD RESEARCH, Vol.58(4) : 166-172, 2023-12 | - |
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