Cited 0 times in
Machine Learning Algorithms for Predicting Treatment Outcomes of Oropharyngeal Cancer After Surgery
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 고윤우 | - |
dc.contributor.author | 김세헌 | - |
dc.contributor.author | 박영민 | - |
dc.contributor.author | 임재열 | - |
dc.contributor.author | 최은창 | - |
dc.date.accessioned | 2024-01-03T01:19:04Z | - |
dc.date.available | 2024-01-03T01:19:04Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 2092-5859 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/197526 | - |
dc.description.abstract | Background and Objectives : This study analyzed data from patients who were diagnosed with human papilloma virus (HPV)-associated oropharyngeal (OPC) and treated surgically to construct a machine learning survival prediction model. Subjects and Method : We retrospectively analyzed the clinico-pathological data of 203 patients with HPV-associated oropharyngeal squamous cell carcinoma (OPSCC) from 2007 to 2015. Results : In the Cox proportional hazard (CPH) model, the c-index values for the training set and the test set were 0.81 and 0.59, respectively. The univariate analysis showed that contralateral lymph nodes (LNs) metastasis, lymphovascular invasion, pN, stage, surgical margin status, histologic grade, pT, and the number of metastatic LNs had significant correlations with survival. Contrastively, the multivariate analysis showed pT and histologic grade to have significant correlation with survival. In the random survival forest model, the c-index values for the training set and the test set were 0.83 and 0.87, respectively. In the DeepSurv model, the cindex values for the training set and the test set were 0.75 and 0.83. Among the three models mentioned above, Random Survival Forest and DeepSurv showed the best performance for predicting the survival of HPV-associated OPSCC patients. Conclusion : We confirmed that a survival prediction model using machine learning and deep learning algorithms showed reasonable survival estimates for HPV-associated OPSCC patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한이비인후과학회 | - |
dc.relation.isPartOf | Korean Journal of Otorhinolaryngology-Head and Neck Surgery | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Machine Learning Algorithms for Predicting Treatment Outcomes of Oropharyngeal Cancer After Surgery | - |
dc.title.alternative | 기계 학습을 이용한 구인두암의 수술 후 치료 예후 예측 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Otorhinolaryngology (이비인후과학교실) | - |
dc.contributor.googleauthor | Dachan Kim | - |
dc.contributor.googleauthor | Se-Heon Kim | - |
dc.contributor.googleauthor | Eun Chang Choi | - |
dc.contributor.googleauthor | Jae-Yol Lim | - |
dc.contributor.googleauthor | Yoon Woo Koh | - |
dc.contributor.googleauthor | Young Min Park | - |
dc.identifier.doi | 10.3342/kjorl-hns.2022.00794 | - |
dc.contributor.localId | A00133 | - |
dc.contributor.localId | A00605 | - |
dc.contributor.localId | A01566 | - |
dc.contributor.localId | A03396 | - |
dc.contributor.localId | A04161 | - |
dc.relation.journalcode | J02089 | - |
dc.identifier.eissn | 2092-6529 | - |
dc.subject.keyword | Deep learning | - |
dc.subject.keyword | Human papilloma virus | - |
dc.subject.keyword | Machine learning | - |
dc.subject.keyword | Survival analysis | - |
dc.contributor.alternativeName | Koh, Yoon Woo | - |
dc.contributor.affiliatedAuthor | 고윤우 | - |
dc.contributor.affiliatedAuthor | 김세헌 | - |
dc.contributor.affiliatedAuthor | 박영민 | - |
dc.contributor.affiliatedAuthor | 임재열 | - |
dc.contributor.affiliatedAuthor | 최은창 | - |
dc.citation.volume | 66 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 241 | - |
dc.citation.endPage | 247 | - |
dc.identifier.bibliographicCitation | Korean Journal of Otorhinolaryngology-Head and Neck Surgery, Vol.66(4) : 241-247, 2023-04 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.