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BMI as a predictor of high fasting blood glucose among people living with HIV in the Asia-Pacific region
DC Field | Value | Language |
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dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2024-01-03T00:48:35Z | - |
dc.date.available | 2024-01-03T00:48:35Z | - |
dc.date.issued | 2023-02 | - |
dc.identifier.issn | 1464-2662 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/197372 | - |
dc.description.abstract | Background: Non-Asian body mass index (BMI) classifications are commonly used as a risk factor for high fasting blood glucose (FBG). We investigated the incidence and factors associated with high FBG among people living with HIV in the Asia-Pacific region, using a World Health Organization BMI classification specific to Asian populations. Methods: This study included people living with HIV enrolled in a longitudinal cohort study from 2003 to 2019, receiving antiretroviral therapy (ART), and without prior tuberculosis. BMI at ART initiation was categorized using Asian BMI classifications: underweight (<18.5 kg/m2 ), normal (18.5-22.9 kg/m2 ), overweight (23-24.9 kg/m2 ), and obese (≥25 kg/m2 ). High FBG was defined as a single post-ART FBG measurement ≥126 mg/dL. Factors associated with high FBG were analyzed using Cox regression models stratified by site. Results: A total of 3939 people living with HIV (63% male) were included. In total, 50% had a BMI in the normal weight range, 23% were underweight, 13% were overweight, and 14% were obese. Median age at ART initiation was 34 years (interquartile range 29-41). Overall, 8% had a high FBG, with an incidence rate of 1.14 per 100 person-years. Factors associated with an increased hazard of high FBG included being obese (≥25 kg/m2 ) compared with normal weight (hazard ratio [HR] = 1.79; 95% confidence interval [CI] 1.31-2.44; p < 0.001) and older age compared with those aged ≤30 years (31-40 years: HR = 1.47; 95% CI 1.08-2.01; 41-50 years: HR = 2.03; 95% CI 1.42-2.90; ≥51 years: HR = 3.19; 95% CI 2.17-4.69; p < 0.001). Conclusion: People living with HIV with BMI >25 kg/m2 were at increased risk of high FBG. This indicates that regular assessments should be performed in those with high BMI, irrespective of the classification used. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley | - |
dc.relation.isPartOf | HIV MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Blood Glucose | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | Fasting | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | HIV Infections* / complications | - |
dc.subject.MESH | HIV Infections* / drug therapy | - |
dc.subject.MESH | HIV Infections* / epidemiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Longitudinal Studies | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Obesity / complications | - |
dc.subject.MESH | Obesity / epidemiology | - |
dc.subject.MESH | Overweight* / complications | - |
dc.subject.MESH | Overweight* / epidemiology | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Thinness / complications | - |
dc.title | BMI as a predictor of high fasting blood glucose among people living with HIV in the Asia-Pacific region | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Dyna Khuon | - |
dc.contributor.googleauthor | Dhanushi Rupasinghe | - |
dc.contributor.googleauthor | Vonthanak Saphonn | - |
dc.contributor.googleauthor | Tsz-Shan Kwong | - |
dc.contributor.googleauthor | Alvina Widhani | - |
dc.contributor.googleauthor | Romanee Chaiwarith | - |
dc.contributor.googleauthor | Penh Sun Ly | - |
dc.contributor.googleauthor | Cuong Duy Do | - |
dc.contributor.googleauthor | Anchalee Avihingsanon | - |
dc.contributor.googleauthor | Suwimon Khusuwan | - |
dc.contributor.googleauthor | Tuti Parwati Merati | - |
dc.contributor.googleauthor | Kinh Van Nguyen | - |
dc.contributor.googleauthor | Nagalingeswaran Kumarasamy | - |
dc.contributor.googleauthor | Yu-Jiun Chan | - |
dc.contributor.googleauthor | Iskandar Azwa | - |
dc.contributor.googleauthor | Oon Tek Ng | - |
dc.contributor.googleauthor | Sasisopin Kiertiburanakul | - |
dc.contributor.googleauthor | Junko Tanuma | - |
dc.contributor.googleauthor | Sanjay Pujari | - |
dc.contributor.googleauthor | Rossana Ditangco | - |
dc.contributor.googleauthor | Fujie Zhang | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.contributor.googleauthor | Yasmin Gani | - |
dc.contributor.googleauthor | Shashikala Sangle | - |
dc.contributor.googleauthor | Jeremy Ross | - |
dc.contributor.googleauthor | Pamina M Gorbach | - |
dc.contributor.googleauthor | Awachana Jiamsakul | - |
dc.contributor.googleauthor | IeDEA Asia-Pacific | - |
dc.identifier.doi | 10.1111/hiv.13351 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J00998 | - |
dc.identifier.eissn | 1468-1293 | - |
dc.identifier.pmid | 35748404 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/10.1111/hiv.13351 | - |
dc.subject.keyword | Asia-Pacific | - |
dc.subject.keyword | BMI | - |
dc.subject.keyword | HIV | - |
dc.subject.keyword | high fasting blood glucose | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | 최준용 | - |
dc.citation.volume | 24 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 139 | - |
dc.citation.endPage | 152 | - |
dc.identifier.bibliographicCitation | HIV MEDICINE, Vol.24(2) : 139-152, 2023-02 | - |
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