Cited 3 times in
Unveiling and harnessing the human gut microbiome in the rising burden of non-communicable diseases during urbanization
DC Field | Value | Language |
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dc.contributor.author | 이혜원 | - |
dc.date.accessioned | 2024-01-03T00:47:07Z | - |
dc.date.available | 2024-01-03T00:47:07Z | - |
dc.date.issued | 2023-12 | - |
dc.identifier.issn | 1949-0976 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/197362 | - |
dc.description.abstract | The world is witnessing a global increase in the urban population, particularly in developing Asian and African countries. Concomitantly, the global burden of non-communicable diseases (NCDs) is rising, markedly associated with the changing landscape of lifestyle and environment during urbanization. Accumulating studies have revealed the role of the gut microbiome in regulating the immune and metabolic homeostasis of the host, which potentially bridges external factors to the host (patho-)physiology. In this review, we discuss the rising incidences of NCDs during urbanization and their links to the compositional and functional dysbiosis of the gut microbiome. In particular, we elucidate the effects of urbanization-associated factors (hygiene/pollution, urbanized diet, lifestyles, the use of antibiotics, and early life exposure) on the gut microbiome underlying the pathogenesis of NCDs. We also discuss the potential and feasibility of microbiome-inspired and microbiome-targeted approaches as novel avenues to counteract NCDs, including fecal microbiota transplantation, diet modulation, probiotics, postbiotics, synbiotics, celobiotics, and precision antibiotics. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Taylor & Francis | - |
dc.relation.isPartOf | GUT MICROBES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Anti-Bacterial Agents / therapeutic use | - |
dc.subject.MESH | Dysbiosis / drug therapy | - |
dc.subject.MESH | Fecal Microbiota Transplantation | - |
dc.subject.MESH | Gastrointestinal Microbiome* / physiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Microbiota* | - |
dc.subject.MESH | Noncommunicable Diseases* / drug therapy | - |
dc.subject.MESH | Noncommunicable Diseases* / therapy | - |
dc.subject.MESH | Prebiotics | - |
dc.subject.MESH | Probiotics* | - |
dc.subject.MESH | Urbanization | - |
dc.title | Unveiling and harnessing the human gut microbiome in the rising burden of non-communicable diseases during urbanization | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Ziyu Huang | - |
dc.contributor.googleauthor | Yue Li | - |
dc.contributor.googleauthor | Heekuk Park | - |
dc.contributor.googleauthor | Martin Ho | - |
dc.contributor.googleauthor | Kanchan Bhardwaj | - |
dc.contributor.googleauthor | Naoki Sugimura | - |
dc.contributor.googleauthor | Hye Won Lee | - |
dc.contributor.googleauthor | Huicui Meng | - |
dc.contributor.googleauthor | Matthias P Ebert | - |
dc.contributor.googleauthor | Kang Chao | - |
dc.contributor.googleauthor | Elke Burgermeister | - |
dc.contributor.googleauthor | Aadra P Bhatt | - |
dc.contributor.googleauthor | Sudarshan A Shetty | - |
dc.contributor.googleauthor | Kai Li | - |
dc.contributor.googleauthor | Weiping Wen | - |
dc.contributor.googleauthor | Tao Zuo | - |
dc.identifier.doi | 10.1080/19490976.2023.2237645 | - |
dc.contributor.localId | A03318 | - |
dc.relation.journalcode | J04211 | - |
dc.identifier.eissn | 1949-0984 | - |
dc.identifier.pmid | 37498052 | - |
dc.subject.keyword | diet | - |
dc.subject.keyword | fecal microbiota transplantation | - |
dc.subject.keyword | non-communicable diseases | - |
dc.subject.keyword | the gut microbiome | - |
dc.subject.keyword | urbanization | - |
dc.contributor.alternativeName | Lee, Hye Won | - |
dc.contributor.affiliatedAuthor | 이혜원 | - |
dc.citation.volume | 15 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 2237645 | - |
dc.identifier.bibliographicCitation | GUT MICROBES, Vol.15(1) : 2237645, 2023-12 | - |
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