Cited 0 times in
Depressive Symptomatology as a Predictor of Cognitive Impairment: Evidence from the Korean Longitudinal Study of Aging (KLOSA), 2006–2020
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤진하 | - |
dc.date.accessioned | 2023-11-07T08:15:44Z | - |
dc.date.available | 2023-11-07T08:15:44Z | - |
dc.date.issued | 2023-10 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196629 | - |
dc.description.abstract | Depressive symptoms are recognized as risk factors for cognitive impairment with intricate underlying biological mechanisms. We explored the link between depressive symptoms and cognitive impairment onset; we also assessed how this association is influenced by educational levels. This study included 5843 individuals aged ≥45 years, comprising 27,908 observations from 2006 to 2020. Based on repeated measurements of each participant, we estimated the association between depressive symptoms and cognitive impairment onset after a 2-year follow-up by using generalized estimating equations. The incidence rate was 9.4% among those individuals without depressive symptoms, which was in contrast with a rate of 21.0% among those individuals experiencing depressive symptoms. The odds ratio (OR) (95% confidence interval [CI]) for the association between depressive symptoms and cognitive impairment onset in the overall sample was 1.61 (1.47-1.76). This association was more pronounced among individuals with higher educational levels. Specifically, the OR (95% CI) of the association between depressive symptoms and cognitive impairment was highest among individuals with a college education (2.60 [1.78-3.81]), and the association was lowest among individuals with elementary or no education levels (1.45 [1.28-1.63]). Our findings highlight the idea that although individuals with higher educational backgrounds exhibit a diminished risk of cognitive impairment, the detrimental impacts of depressive symptoms on cognitive performance are particularly more pronounced within this group. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI AG | - |
dc.relation.isPartOf | BIOMEDICINES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Depressive Symptomatology as a Predictor of Cognitive Impairment: Evidence from the Korean Longitudinal Study of Aging (KLOSA), 2006–2020 | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine (예방의학교실) | - |
dc.contributor.googleauthor | Seong-Uk Baek | - |
dc.contributor.googleauthor | Jin-Ha Yoon | - |
dc.identifier.doi | 10.3390/biomedicines11102713 | - |
dc.contributor.localId | A04616 | - |
dc.relation.journalcode | J03914 | - |
dc.identifier.eissn | 2227-9059 | - |
dc.identifier.pmid | 37893087 | - |
dc.subject.keyword | cognitive health | - |
dc.subject.keyword | dementia | - |
dc.subject.keyword | depression | - |
dc.subject.keyword | epidemiology | - |
dc.subject.keyword | neurodegenerative disease | - |
dc.subject.keyword | repeated measures analysis | - |
dc.contributor.alternativeName | Yoon, Jin Ha | - |
dc.contributor.affiliatedAuthor | 윤진하 | - |
dc.citation.volume | 11 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 2713 | - |
dc.identifier.bibliographicCitation | BIOMEDICINES, Vol.11(10) : 2713, 2023-10 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.