Cited 0 times in
Effects of depression on medication adherence in HIV/AIDS patients: Korea HIV/AIDS cohort study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김현창 | - |
dc.date.accessioned | 2023-10-19T05:39:41Z | - |
dc.date.available | 2023-10-19T05:39:41Z | - |
dc.date.issued | 2023-10 | - |
dc.identifier.issn | 1876-0341 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196235 | - |
dc.description.abstract | Background: The number of people with HIV/AIDS has consistently increased in Korea since the first case of HIV/AIDS infection was reported in 1985. The depressive symptoms of patients with HIV/AIDS may lead to medication non-adherence. This study sought to investigate the cross-sectional and longitudinal association between depression and antiretroviral treatment adherence in the Korean HIV/AIDS population. Methods: We included participants of the Korea HIV/AIDS cohort study between 2009 and 2017. All information was collected at the enrollment and every annual visit, including sociodemographic characteristics, health-related behaviors, HIV/AIDS infection-related factors, depression score, and frequency of skipped medication. We performed a cross-sectional analysis of 601 participants registered between 2009 and 2017. Longitudinal data were evaluated by panel regression analysis in 515 patients who registered from 2009 to 2013. Results: In cross-sectional analysis, the HIV/AIDS patients with depressive symptoms were more likely to be non-adherent (adjusted OR = 0.52, 95 % CI 0.34, 0.79, p = 0.002). Medication adherence was significantly associated with a health-related lifestyle; the adjusted odds ratio of the non-smoking and non-drinking group was 1.75 (95 % CI 1.05, 2.90, p = 0.031). The longitudinal panel regression model revealed a significant negative impact of depression on medication adherence (adjusted OR = 0.50, 95 % CI 0.30, 0.84, p = 0.009). Non-smoking and non-drinking participants were 2.31 times more likely to adhere to antiretroviral treatment (95 % CI 1.29, 4.15, p = 0.005). Conclusions: Our finding of depression and lifestyle modifications being significant contributors underscore the importance of proactive interventions to optimize the treatment outcomes of PLWH. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF INFECTION AND PUBLIC HEALTH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Acquired Immunodeficiency Syndrome* / complications | - |
dc.subject.MESH | Acquired Immunodeficiency Syndrome* / drug therapy | - |
dc.subject.MESH | Acquired Immunodeficiency Syndrome* / epidemiology | - |
dc.subject.MESH | Anti-Retroviral Agents / therapeutic use | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Depression / epidemiology | - |
dc.subject.MESH | HIV Infections* / complications | - |
dc.subject.MESH | HIV Infections* / drug therapy | - |
dc.subject.MESH | HIV Infections* / epidemiology | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Medication Adherence | - |
dc.subject.MESH | Republic of Korea / epidemiology | - |
dc.title | Effects of depression on medication adherence in HIV/AIDS patients: Korea HIV/AIDS cohort study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine (예방의학교실) | - |
dc.contributor.googleauthor | Kyung Sun Oh | - |
dc.contributor.googleauthor | Jin Soo Lee | - |
dc.contributor.googleauthor | Hyeon Chang Kim | - |
dc.contributor.googleauthor | Hye-Young Kang | - |
dc.contributor.googleauthor | Ju-Yeun Lee | - |
dc.contributor.googleauthor | Euna Han | - |
dc.identifier.doi | 10.1016/j.jiph.2023.07.018 | - |
dc.contributor.localId | A01142 | - |
dc.relation.journalcode | J04249 | - |
dc.identifier.eissn | 1876-035X | - |
dc.identifier.pmid | 37573850 | - |
dc.subject.keyword | AIDS | - |
dc.subject.keyword | Cross-sectional analysis | - |
dc.subject.keyword | Depression | - |
dc.subject.keyword | Medication adherence | - |
dc.subject.keyword | Panel-data analysis | - |
dc.contributor.alternativeName | Kim, Hyeon Chang | - |
dc.contributor.affiliatedAuthor | 김현창 | - |
dc.citation.volume | 16 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1598 | - |
dc.citation.endPage | 1605 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INFECTION AND PUBLIC HEALTH, Vol.16(10) : 1598-1605, 2023-10 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.