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Biomarker-Based Assessment Model for Detecting Sepsis: A Retrospective Cohort Study
DC Field | Value | Language |
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dc.contributor.author | 설창환 | - |
dc.contributor.author | 정경수 | - |
dc.date.accessioned | 2023-10-19T05:38:42Z | - |
dc.date.available | 2023-10-19T05:38:42Z | - |
dc.date.issued | 2023-08 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196231 | - |
dc.description.abstract | The concept of the quick sequential organ failure assessment (qSOFA) simplifies sepsis detection, and the next SOFA should be analyzed subsequently to diagnose sepsis. However, it does not include the concept of suspected infection. Thus, we simply developed a biomarker-based assessment model for detecting sepsis (BADS). We retrospectively reviewed the electronic health records of patients admitted to the intensive care unit (ICU) of a 2000-bed university tertiary referral hospital in South Korea. A total of 989 patients were enrolled, with 77.4% (n = 765) of them having sepsis. The patients were divided into a ratio of 8:2 and assigned to a training and a validation set. We used logistic regression analysis and the Hosmer-Lemeshow test to derive the BADS and assess the model. BADS was developed by analyzing the variables and then assigning weights to the selected variables: mean arterial pressure, shock index, lactate, and procalcitonin. The area under the curve was 0.754, 0.615, 0.763, and 0.668 for BADS, qSOFA, SOFA, and acute physiology and chronic health evaluation (APACHE) II, respectively, showing that BADS is not inferior in sepsis prediction compared with SOFA. BADS could be a simple scoring method to detect sepsis in critically ill patients quickly at the bedside. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | MDPI | - |
dc.relation.isPartOf | JOURNAL OF PERSONALIZED MEDICINE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Biomarker-Based Assessment Model for Detecting Sepsis: A Retrospective Cohort Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Bo Ra Yoon | - |
dc.contributor.googleauthor | Chang Hwan Seol | - |
dc.contributor.googleauthor | In Kyung Min | - |
dc.contributor.googleauthor | Min Su Park | - |
dc.contributor.googleauthor | Ji Eun Park | - |
dc.contributor.googleauthor | Kyung Soo Chung | - |
dc.identifier.doi | 10.3390/jpm13081195 | - |
dc.contributor.localId | A05999 | - |
dc.contributor.localId | A03570 | - |
dc.relation.journalcode | J04078 | - |
dc.identifier.eissn | 2075-4426 | - |
dc.identifier.pmid | 37623446 | - |
dc.subject.keyword | infection | - |
dc.subject.keyword | intensive care unit | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | quick sequential organ failure assessment | - |
dc.subject.keyword | septic shock | - |
dc.contributor.alternativeName | Seol, Chang Hwan | - |
dc.contributor.affiliatedAuthor | 설창환 | - |
dc.contributor.affiliatedAuthor | 정경수 | - |
dc.citation.volume | 13 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 1195 | - |
dc.identifier.bibliographicCitation | JOURNAL OF PERSONALIZED MEDICINE, Vol.13(8) : 1195, 2023-08 | - |
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