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Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 권아름 | - |
dc.contributor.author | 김호성 | - |
dc.contributor.author | 서정환 | - |
dc.contributor.author | 정세용 | - |
dc.contributor.author | 채현욱 | - |
dc.date.accessioned | 2023-08-23T00:07:34Z | - |
dc.date.available | 2023-08-23T00:07:34Z | - |
dc.date.issued | 2023-06 | - |
dc.identifier.issn | 2287-1012 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/196162 | - |
dc.description.abstract | Thyroid hormone plays a vital role in regulating human metabolism. They affect the functions of major organs, such as the brain, liver, skeletal muscle, and heart. Hypothyroidism can lead to dilated cardiomyopathy and decreased heart function. In this report, we describe a case of a teenage boy who developed dilated cardiomyopathy due to hypothyroidism and was considered to undergo heart transplantation. Levothyroxine monotherapy was initiated but produced no improvement. Thereafter, a combination therapy of liothyronine and levothyroxine was administered, and heart function was gradually restored; he recovered completely after 6 months. Cardiac myocytes respond more specifically to liothyronine than to levothyroxine. Therefore, we suggest that liothyronine and levothyroxine combination therapy should be considered rather than levothyroxine monotherapy for hypothyroidism accompanied by heart disease. © 2023 Annals of Pediatric Endocrinology & Metabolism. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Society of Pediatric Endocrinology | - |
dc.relation.isPartOf | ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Combination therapy of liothyronine and levothyroxine for hypothyroidism-induced dilated cardiomyopathy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아과학교실) | - |
dc.contributor.googleauthor | Youngha Choi | - |
dc.contributor.googleauthor | Se Yong Jung | - |
dc.contributor.googleauthor | Jung Min Park | - |
dc.contributor.googleauthor | Junghwan Suh | - |
dc.contributor.googleauthor | Eun Jung Shin | - |
dc.contributor.googleauthor | Hyun Wook Chae | - |
dc.contributor.googleauthor | Ho-Seong Kim | - |
dc.contributor.googleauthor | Ahreum Kwon | - |
dc.identifier.doi | 10.6065/apem.2142218.109 | - |
dc.contributor.localId | A00228 | - |
dc.contributor.localId | A01184 | - |
dc.contributor.localId | A05629 | - |
dc.contributor.localId | A03628 | - |
dc.contributor.localId | A04026 | - |
dc.relation.journalcode | J00175 | - |
dc.identifier.eissn | 2287-1292 | - |
dc.identifier.pmid | 35718890 | - |
dc.subject.keyword | Dilated cardiomyopathy | - |
dc.subject.keyword | Heart failure | - |
dc.subject.keyword | Hypothyroidism | - |
dc.subject.keyword | Levothyroxine | - |
dc.subject.keyword | Thyroid hormone | - |
dc.subject.keyword | Triiodothyronine | - |
dc.contributor.alternativeName | Kwon, Ah Reum | - |
dc.contributor.affiliatedAuthor | 권아름 | - |
dc.contributor.affiliatedAuthor | 김호성 | - |
dc.contributor.affiliatedAuthor | 서정환 | - |
dc.contributor.affiliatedAuthor | 정세용 | - |
dc.contributor.affiliatedAuthor | 채현욱 | - |
dc.citation.volume | 28 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 144 | - |
dc.citation.endPage | 148 | - |
dc.identifier.bibliographicCitation | ANNALS OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, Vol.28(2) : 144-148, 2023-06 | - |
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