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B-acute lymphoblastic leukemia/lymphoma (B-ALL) with precedent or concurrent myelodysplastic syndrome (MDS) with deletion 5q
DC Field | Value | Language |
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dc.date.accessioned | 2023-08-09T02:42:51Z | - |
dc.date.available | 2023-08-09T02:42:51Z | - |
dc.date.issued | 2017-08 | - |
dc.identifier.issn | 1868-9256 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195770 | - |
dc.description.abstract | Progression to acute leukemia is an inherited feature of myelodysplastic syndrome (MDS). While majority of acute leukemia cases in this setting is acute myeloid leukemia (AML), rare cases of acute B-lymphoblastic leukemia/lymphoma (B-ALL) also exist. Therefore, detection of increased blasts in a patient with MDS should not be equated with a diagnosis of AML; full immunophenotyping of blasts is required. Previous reports indicate that dysplastic myeloid cells and B-lymphoblasts belong to the same clone. However, dysplastic myeloid cells and B-lymphoblasts could be clonally unrelated. Decitabine in addition to hyperCVAD (fractionated cyclophosphamide, vincristine, doxorubicin and dexamethasone alternating with high-dose methotrexate and cytarabine) could be a good treatment option in this particular clinical setting. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Springer | - |
dc.relation.isPartOf | JOURNAL OF HEMATOPATHOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | B-acute lymphoblastic leukemia/lymphoma (B-ALL) with precedent or concurrent myelodysplastic syndrome (MDS) with deletion 5q | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pathology (병리학교실) | - |
dc.contributor.googleauthor | Jin Woo Joo | - |
dc.contributor.googleauthor | Sergej Konoplev | - |
dc.contributor.googleauthor | Timothy J. McDonnell | - |
dc.contributor.googleauthor | Chi Young Ok | - |
dc.identifier.doi | 10.1007/s12308-017-0298-7 | - |
dc.relation.journalcode | J04473 | - |
dc.identifier.eissn | 1865-5785 | - |
dc.identifier.url | https://link.springer.com/article/10.1007/s12308-017-0298-7 | - |
dc.subject.keyword | MDS | - |
dc.subject.keyword | B-all | - |
dc.subject.keyword | Del (5q) | - |
dc.citation.volume | 10 | - |
dc.citation.startPage | 75 | - |
dc.citation.endPage | 80 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HEMATOPATHOLOGY, Vol.10 : 75-80, 2017-08 | - |
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