Cited 25 times in
Impact of age and sex on left ventricular function determined by coronary computed tomographic angiography: results from the prospective multicentre CONFIRM study
DC Field | Value | Language |
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dc.contributor.author | 장혁재 | - |
dc.date.accessioned | 2023-08-09T02:36:59Z | - |
dc.date.available | 2023-08-09T02:36:59Z | - |
dc.date.issued | 2017-09 | - |
dc.identifier.issn | 2047-2404 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/195682 | - |
dc.description.abstract | Background: Left ventricular (LV) volumetric and functional parameters measured with cardiac computed tomography (cardiac CT) augment risk prediction and discrimination for future mortality. Gender- and age-specific standard values for LV dimensions and systolic function obtained by 64-slice cardiac CT are lacking. Methods and results: 1155 patients from the Coronary CT Angiography EvaluatioN For Clinical Outcomes: An InteRnational Multicenter registry (54.5% males, mean age 53.1 ± 12.4 years, range: 18-92 years) without known coronary artery disease (CAD), structural heart disease, diabetes, or hypertension who underwent cardiac CT for various indications were categorized according to age and sex. A cardiac CT data acquisition protocol was used that allowed volumetric measuring of LV function. Image interpretation was performed at each site. Patients with significant CAD (>50% stenosis) on cardiac CT were excluded from the analysis. Overall, mean left ventricular ejection fraction (LVEF) was higher in women when compared with men (66.6 ± 7.7% vs. 64.6 ± 8.1%, P < 0.001). This gender-difference in overall LVEF was caused by a significantly higher LVEF in women ≥70 years when compared with men ≥70 years (69.95 ± 8.89% vs. 65.50 ± 9.42%, P = 0.004). Accordingly, a significant increase in LVEF was observed with age (P = 0.005 for males and P < 0.001 for females), which was more pronounced in females (5.21%) than in males (2.6%). LV end-diastolic volume decreased in females from 122.48 ± 27.87 (<40 years) to 95.56 ± 23.17 (>70 years; P < 0.001) and in males from 155.22 ± 35.07 (<40 years) to 130.26 ± 27.18 (>70 years; P < 0.001). Conclusion: Our findings indicate that the LV undergoes a lifelong remodelling and highlight the need for age and gender adjusted reference values. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Oxford University Press | - |
dc.relation.isPartOf | EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Age Factors | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Analysis of Variance | - |
dc.subject.MESH | Cohort Studies | - |
dc.subject.MESH | Computed Tomography Angiography / methods* | - |
dc.subject.MESH | Coronary Angiography / methods* | - |
dc.subject.MESH | Coronary Artery Disease / diagnostic imaging* | - |
dc.subject.MESH | Coronary Artery Disease / mortality* | - |
dc.subject.MESH | Coronary Artery Disease / physiopathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Registries | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Severity of Illness Index | - |
dc.subject.MESH | Sex Factors | - |
dc.subject.MESH | Statistics, Nonparametric | - |
dc.subject.MESH | Survival Rate | - |
dc.subject.MESH | Ventricular Dysfunction, Left / diagnostic imaging* | - |
dc.subject.MESH | Ventricular Dysfunction, Left / mortality | - |
dc.subject.MESH | Ventricular Dysfunction, Left / physiopathology | - |
dc.title | Impact of age and sex on left ventricular function determined by coronary computed tomographic angiography: results from the prospective multicentre CONFIRM study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Catherine Gebhard | - |
dc.contributor.googleauthor | Ronny R Buechel | - |
dc.contributor.googleauthor | Barbara E Stähli | - |
dc.contributor.googleauthor | Heidi Gransar | - |
dc.contributor.googleauthor | Stephan Achenbach | - |
dc.contributor.googleauthor | Daniel S Berman | - |
dc.contributor.googleauthor | Matthew J Budoff | - |
dc.contributor.googleauthor | Tracy Q Callister | - |
dc.contributor.googleauthor | Benjamin Chow | - |
dc.contributor.googleauthor | Allison Dunning | - |
dc.contributor.googleauthor | Mouaz H Al-Mallah | - |
dc.contributor.googleauthor | Filippo Cademartiri | - |
dc.contributor.googleauthor | Kavitha Chinnaiyan | - |
dc.contributor.googleauthor | Ronen Rubinshtein | - |
dc.contributor.googleauthor | Hugo Marques | - |
dc.contributor.googleauthor | Augustin DeLago | - |
dc.contributor.googleauthor | Todd C Villines | - |
dc.contributor.googleauthor | Martin Hadamitzky | - |
dc.contributor.googleauthor | Joerg Hausleiter | - |
dc.contributor.googleauthor | Leslee J Shaw | - |
dc.contributor.googleauthor | Ricardo C Cury | - |
dc.contributor.googleauthor | Gudrun Feuchtner | - |
dc.contributor.googleauthor | Yong-Jin Kim | - |
dc.contributor.googleauthor | Erica Maffei | - |
dc.contributor.googleauthor | Gilbert Raff | - |
dc.contributor.googleauthor | Gianluca Pontone | - |
dc.contributor.googleauthor | Daniele Andreini | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.contributor.googleauthor | Jonathon Leipsic | - |
dc.contributor.googleauthor | James K Min | - |
dc.contributor.googleauthor | Philipp A Kaufmann | - |
dc.identifier.doi | 10.1093/ehjci/jew142 | - |
dc.contributor.localId | A03490 | - |
dc.relation.journalcode | J00806 | - |
dc.identifier.eissn | 2047-2412 | - |
dc.identifier.pmid | 27461207 | - |
dc.identifier.url | https://academic.oup.com/ehjcimaging/article/18/9/990/3060607 | - |
dc.subject.keyword | cardiac computed tomography | - |
dc.subject.keyword | left ventricular ejection fraction | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | 장혁재 | - |
dc.citation.volume | 18 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 990 | - |
dc.citation.endPage | 1000 | - |
dc.identifier.bibliographicCitation | EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING, Vol.18(9) : 990-1000, 2017-09 | - |
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