0 133

Cited 0 times in

Y chromosomal deletion pattern in Koreans inhabiting Jeju Island

Authors
 Ji Hyun Lee  ;  Hong Xuan Jin  ;  Sohee Cho  ;  Han Na Kim  ;  Hee Jin Seo  ;  Kyoung-Jin Shin  ;  Dong Hoon Shin  ;  Soong Deok Lee 
Citation
 ANTHROPOLOGISCHER ANZEIGER, Vol.74(3) : 177-182, 2017-09 
Journal Title
ANTHROPOLOGISCHER ANZEIGER
ISSN
 0003-5548 
Issue Date
2017-09
MeSH
Chromosome Deletion* ; Chromosomes, Human, Y / genetics* ; Genetics, Population ; Humans ; Male ; Microsatellite Repeats / genetics* ; Republic of Korea / epidemiology
Abstract
Mutations occur in Y chromosome genes similar to autosomal genes. However, unlike autosomal genes, Y chromosome genes do not undergo recombination, which produce distinctive characteristics and distribution patterns in different geographic regions. Therefore, detailed analysis of mutations of Y chromosome genes might provide information for personal identification or analysis of phylogenetic history. In Y-STR (short tandem repeat) analysis tests on 668 habitants of Jeju Island, the largest island in the Korean peninsula located apart from the mainland, a deletion at DYS448 was found in 10 samples. The length of deletion was estimated by confirming specific Sequence Tagged Site (STS) markers ranging from G66018 to sY1201. Patterns found were similar to those of the Kalmyks, a tribe that has had strong social and genetic influences in Jeju Island in the past. Historically from 1273 on, Jeju Island was governed by Mongolian for about one hundred years. The results of this study suggest such historical aspects affected the genetic composition of people living in Jeju Island. Furthermore, previous reports showed that Y chromosomal deletions and region specific Y chromosomal mutations depended on regional differences. This study may be useful for a better understanding of the genetic structure of Jeju habitants as well as Korean population for the purpose of forensic practice and population genetics.
Full Text
https://www.schweizerbart.de/papers/anthranz/detail/74/87580/
DOI
10.1127/anthranz/2017/0669
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Forensic Medicine (법의학과) > 1. Journal Papers
Yonsei Authors
Shin, Kyoung Jin(신경진) ORCID logo https://orcid.org/0000-0002-1059-9665
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/195621
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links